VFUS_ORFN2
ID VFUS_ORFN2 Reviewed; 89 AA.
AC P26654;
DT 01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1992, sequence version 1.
DT 25-MAY-2022, entry version 50.
DE RecName: Full=10 kDa fusion protein;
OS Orf virus (strain NZ2) (OV NZ-2).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Chitovirales; Poxviridae; Chordopoxvirinae; Parapoxvirus.
OX NCBI_TaxID=10259;
OH NCBI_TaxID=9925; Capra hircus (Goat).
OH NCBI_TaxID=9606; Homo sapiens (Human).
OH NCBI_TaxID=9940; Ovis aries (Sheep).
RN [1]
RP NUCLEOTIDE SEQUENCE.
RX PubMed=2033392; DOI=10.1099/0022-1317-72-5-1177;
RA Naase M., Nicholson B.H., Fraser K.M., Mercer A.A., Robinson A.J.;
RT "An orf virus sequence showing homology to the 14K 'fusion' protein of
RT vaccinia virus.";
RL J. Gen. Virol. 72:1177-1181(1991).
CC -!- SUBUNIT: Homotrimer, covalently linked. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000250|UniProtKB:P26312}.
CC -!- SIMILARITY: Belongs to the poxviruses fusion protein family.
CC {ECO:0000305}.
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DR PIR; A38711; WMVZRF.
DR SMR; P26654; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0019031; C:viral envelope; IEA:InterPro.
DR GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0019064; P:fusion of virus membrane with host plasma membrane; IEA:InterPro.
DR GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR GO; GO:0019062; P:virion attachment to host cell; IEA:UniProtKB-KW.
DR InterPro; IPR003436; Chordopox_Fusion/A27.
DR Pfam; PF02346; Vac_Fusion; 1.
DR PRINTS; PR01847; VIRALFUSION.
PE 3: Inferred from homology;
KW Glycoprotein; Host-virus interaction; Late protein; Membrane;
KW Viral attachment to host cell; Virion; Virus entry into host cell.
FT CHAIN 1..89
FT /note="10 kDa fusion protein"
FT /id="PRO_0000099216"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..26
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 18
FT /note="N-linked (GlcNAc...) asparagine; by host"
FT /evidence="ECO:0000255"
SQ SEQUENCE 89 AA; 10050 MW; A0105456AAC8F8E9 CRC64;
MDENDGENLL TQPDDTGNST NGVYAAGAPT KESVEERLVS LLDSYKTITD CCRETGNRLD
RLERHLESLR KALLDLNRKI DVQTGYSRY