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VFUS_ORFN2
ID   VFUS_ORFN2              Reviewed;          89 AA.
AC   P26654;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1992, sequence version 1.
DT   25-MAY-2022, entry version 50.
DE   RecName: Full=10 kDa fusion protein;
OS   Orf virus (strain NZ2) (OV NZ-2).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Parapoxvirus.
OX   NCBI_TaxID=10259;
OH   NCBI_TaxID=9925; Capra hircus (Goat).
OH   NCBI_TaxID=9606; Homo sapiens (Human).
OH   NCBI_TaxID=9940; Ovis aries (Sheep).
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=2033392; DOI=10.1099/0022-1317-72-5-1177;
RA   Naase M., Nicholson B.H., Fraser K.M., Mercer A.A., Robinson A.J.;
RT   "An orf virus sequence showing homology to the 14K 'fusion' protein of
RT   vaccinia virus.";
RL   J. Gen. Virol. 72:1177-1181(1991).
CC   -!- SUBUNIT: Homotrimer, covalently linked. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000250|UniProtKB:P26312}.
CC   -!- SIMILARITY: Belongs to the poxviruses fusion protein family.
CC       {ECO:0000305}.
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DR   PIR; A38711; WMVZRF.
DR   SMR; P26654; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0019031; C:viral envelope; IEA:InterPro.
DR   GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0019064; P:fusion of virus membrane with host plasma membrane; IEA:InterPro.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   GO; GO:0019062; P:virion attachment to host cell; IEA:UniProtKB-KW.
DR   InterPro; IPR003436; Chordopox_Fusion/A27.
DR   Pfam; PF02346; Vac_Fusion; 1.
DR   PRINTS; PR01847; VIRALFUSION.
PE   3: Inferred from homology;
KW   Glycoprotein; Host-virus interaction; Late protein; Membrane;
KW   Viral attachment to host cell; Virion; Virus entry into host cell.
FT   CHAIN           1..89
FT                   /note="10 kDa fusion protein"
FT                   /id="PRO_0000099216"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        10..26
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        18
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   89 AA;  10050 MW;  A0105456AAC8F8E9 CRC64;
     MDENDGENLL TQPDDTGNST NGVYAAGAPT KESVEERLVS LLDSYKTITD CCRETGNRLD
     RLERHLESLR KALLDLNRKI DVQTGYSRY
 
 
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