VG24_BPMD2
ID VG24_BPMD2 Reviewed; 134 AA.
AC O64218;
DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 12-AUG-2020, entry version 49.
DE RecName: Full=Tail assembly protein Gp24 {ECO:0000305};
DE AltName: Full=Gene product 24;
DE AltName: Full=Gp24;
DE AltName: Full=Minor tail protein Gp24 {ECO:0000305};
GN Name=24;
OS Mycobacterium phage D29 (Mycobacteriophage D29).
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Caudovirales; Siphoviridae; Fromanvirus.
OX NCBI_TaxID=28369;
OH NCBI_TaxID=1763; Mycobacterium.
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=9636706; DOI=10.1006/jmbi.1997.1610;
RA Ford M.E., Sarkis G.J., Belanger A.E., Hendrix R.W., Hatfull G.F.;
RT "Genome structure of mycobacteriophage D29: implications for phage
RT evolution.";
RL J. Mol. Biol. 279:143-164(1998).
CC -!- FUNCTION: Promotes tail assembly by creating a scaffold for the tail
CC tube proteins. The tail assembly proteins Gp24 and Gp25 would wrap the
CC linear tape measure protein to create a tail assembly scaffold. It
CC would allow polymerization of tail tube protein during which Gp24 and
CC Gp25 are released and therefore are absent from the mature virion. The
CC tail assembly protein Gp25 is produced by a rare -1 ribosomal
CC frameshift. The ratio Gp24/Gp25 is important for proper tail assembly.
CC {ECO:0000250|UniProtKB:P03734}.
CC -!- SUBUNIT: Interacts with tail assembly protein Gp25 and tape measure
CC protein. {ECO:0000250|UniProtKB:P03734}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Ribosomal frameshifting; Named isoforms=2;
CC Name=Tail assembly protein Gp24;
CC IsoId=O64218-1; Sequence=Displayed;
CC Name=Tail assembly protein Gp25;
CC IsoId=O64219-1; Sequence=External;
CC -!- MISCELLANEOUS: [Isoform Tail assembly protein Gp24]: Produced by
CC conventional translation.
CC -!- SIMILARITY: Belongs to the L5likevirus tail assembly protein family.
CC {ECO:0000305}.
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DR EMBL; AF022214; AAC18465.1; -; Genomic_DNA.
DR PIR; F72802; F72802.
DR RefSeq; NP_046840.1; NC_001900.1. [O64218-1]
DR GeneID; 1261597; -.
DR KEGG; vg:1261597; -.
DR Proteomes; UP000002131; Genome.
DR GO; GO:0098003; P:viral tail assembly; IEA:UniProtKB-KW.
DR InterPro; IPR020132; Gp24/Gp25.
DR Pfam; PF17388; GP24_25; 1.
PE 3: Inferred from homology;
KW Reference proteome; Ribosomal frameshifting; Viral release from host cell;
KW Viral tail assembly.
FT CHAIN 1..134
FT /note="Tail assembly protein Gp24"
FT /id="PRO_0000164736"
SQ SEQUENCE 134 AA; 15175 MW; B036DF4A3216A0EC CRC64;
MTNVFTIDAF REEVKKKYEP VTIGISEDVT VELKPLLKLG QKAREAVVEA VKEVEDIPDI
DEDDEEAEEL VDEYSLRICE IVAKVFRLIA TKPKKLIAAL DEEEDPRIRA ELYATVLRTW
MVETQLGEAA PSPS