ID   VG24_BPML5              Reviewed;         132 AA.
AC   Q05231;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   02-JUN-2021, entry version 54.
DE   RecName: Full=Tail assembly protein Gp24 {ECO:0000305};
DE   AltName: Full=Gene product 24;
DE   AltName: Full=Gp24;
DE   AltName: Full=Minor tail protein Gp24 {ECO:0000305};
GN   Name=24;
OS   Mycobacterium phage L5 (Mycobacteriophage L5).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Siphoviridae; Fromanvirus.
OX   NCBI_TaxID=31757;
OH   NCBI_TaxID=1763; Mycobacterium.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=8459766; DOI=10.1111/j.1365-2958.1993.tb01131.x;
RA   Hatfull G.F., Sarkis G.J.;
RT   "DNA sequence, structure and gene expression of mycobacteriophage L5: a
RT   phage system for mycobacterial genetics.";
RL   Mol. Microbiol. 7:395-405(1993).
RN   [2]
RP   RIBOSOMAL FRAMESHIFT.
RX   PubMed=15469818; DOI=10.1016/j.molcel.2004.09.006;
RA   Xu J., Hendrix R.W., Duda R.L.;
RT   "Conserved translational frameshift in dsDNA bacteriophage tail assembly
RT   genes.";
RL   Mol. Cell 16:11-21(2004).
CC   -!- FUNCTION: Promotes tail assembly by creating a scaffold for the tail
CC       tube proteins. The tail assembly proteins Gp24 and Gp25 would wrap the
CC       linear tape measure protein to create a tail assembly scaffold. It
CC       would allow polymerization of tail tube protein during which Gp24 and
CC       Gp25 are released and therefore are absent from the mature virion. The
CC       tail assembly protein Gp25 is produced by a rare -1 ribosomal
CC       frameshift. The ratio Gp24/Gp25 is important for proper tail assembly.
CC       {ECO:0000250|UniProtKB:P03734}.
CC   -!- SUBUNIT: Interacts with tail assembly protein Gp25 and tape measure
CC       protein. {ECO:0000250|UniProtKB:P03734}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Ribosomal frameshifting; Named isoforms=2;
CC         Comment=A readthrough event might also occur in addition to the
CC         frameshifting event. {ECO:0000269|PubMed:15469818};
CC       Name=Tail assembly protein Gp24 {ECO:0000269|PubMed:15469818};
CC         IsoId=Q05231-1; Sequence=Displayed;
CC       Name=Tail assembly protein Gp25 {ECO:0000269|PubMed:15469818};
CC         IsoId=Q05232-1; Sequence=External;
CC   -!- MISCELLANEOUS: [Isoform Tail assembly protein Gp24]: Produced by
CC       conventional translation.
CC   -!- SIMILARITY: Belongs to the L5likevirus tail assembly protein family.
CC       {ECO:0000305}.
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DR   EMBL; Z18946; CAA79400.1; -; Genomic_DNA.
DR   PIR; S30969; S30969.
DR   RefSeq; NP_039688.1; NC_001335.1. [Q05231-1]
DR   GeneID; 2942950; -.
DR   KEGG; vg:2942950; -.
DR   Proteomes; UP000002123; Genome.
DR   GO; GO:0098003; P:viral tail assembly; IEA:UniProtKB-KW.
DR   InterPro; IPR020132; Gp24/Gp25.
DR   Pfam; PF17388; GP24_25; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Ribosomal frameshifting; Viral release from host cell;
KW   Viral tail assembly.
FT   CHAIN           1..132
FT                   /note="Tail assembly protein Gp24"
FT                   /id="PRO_0000164737"
SQ   SEQUENCE   132 AA;  14847 MW;  192949FF92CD3FB8 CRC64;
     MTNVFTIDAF REEVKKKYAP VLIGLSDDVT VELKPLLKLG QKAREAVVEV FKEFADIPDL
     EEDDDDELVD EYSLQVCDII AKAFRLIATK PKKLIAALDE EPDPRIRAEL YAAVLNTWKR
     ETQLGEAAPS PS