ID   VG4_BPB03               Reviewed;         125 AA.
AC   Q37884;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Late genes activator;
DE   AltName: Full=Early protein GP4;
GN   Name=4;
OS   Bacillus phage B103 (Bacteriophage B103).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Salasmaviridae; Picovirinae; Beecentumtrevirus.
OX   NCBI_TaxID=10778;
OH   NCBI_TaxID=1423; Bacillus subtilis.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=9358052; DOI=10.1016/s0378-1119(97)00363-6;
RA   Pecenkova T., Benes V., Paces J., Vlcek C., Paces V.;
RT   "Bacteriophage B103: complete DNA sequence of its genome and relationship
RT   to other Bacillus phages.";
RL   Gene 199:157-163(1997).
CC   -!- FUNCTION: This protein is believed to be a positive regulator of late
CC       transcription. It may function as a sigma-like component of the host
CC       RNA polymerase. Binds to a region of the A3 promoter located between
CC       nucleotides -50 and -100 relative to the transcription start site, that
CC       presents a sequence-directed curvature. Full induction of this
CC       curvature is needed for the transcription activation process (By
CC       similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the podoviruses GP4 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X99260; CAA67651.1; -; Genomic_DNA.
DR   RefSeq; NP_690637.1; NC_004165.1.
DR   SMR; Q37884; -.
DR   GeneID; 955360; -.
DR   KEGG; vg:955360; -.
DR   Proteomes; UP000000971; Genome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:InterPro.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.70.3560; -; 1.
DR   InterPro; IPR038246; Phi-29-like_sf.
DR   InterPro; IPR008771; Phi-29_GP4.
DR   Pfam; PF05464; Phi-29_GP4; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-directed RNA polymerase; Early protein;
KW   Nucleotidyltransferase; Sigma factor; Transcription;
KW   Transcription regulation; Transferase.
FT   CHAIN           1..125
FT                   /note="Late genes activator"
FT                   /id="PRO_0000106558"
FT   DNA_BIND        77..96
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   125 AA;  14915 MW;  678781CE7726FC59 CRC64;
     MPRTARGIYH NLKESEYVVS NGDATFFFSS ELYLNKFLDG YQKHREEFNK KINRITDTPL
     NMDMLADITF YSNVEKRGFH TWLKGCNASW QEIHVYALRT MTKPCTQNWS RIRKPKLAER
     RKNMV