ID   CAIE_ECOSM              Reviewed;         196 AA.
AC   B1LFW8;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   29-APR-2008, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Carnitine operon protein CaiE {ECO:0000255|HAMAP-Rule:MF_01525};
GN   Name=caiE {ECO:0000255|HAMAP-Rule:MF_01525};
GN   OrderedLocusNames=EcSMS35_0036;
OS   Escherichia coli (strain SMS-3-5 / SECEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=439855;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SMS-3-5 / SECEC;
RX   PubMed=18708504; DOI=10.1128/jb.00661-08;
RA   Fricke W.F., Wright M.S., Lindell A.H., Harkins D.M., Baker-Austin C.,
RA   Ravel J., Stepanauskas R.;
RT   "Insights into the environmental resistance gene pool from the genome
RT   sequence of the multidrug-resistant environmental isolate Escherichia coli
RT   SMS-3-5.";
RL   J. Bacteriol. 190:6779-6794(2008).
CC   -!- FUNCTION: Overproduction of CaiE stimulates the activity of CaiB and
CC       CaiD. {ECO:0000255|HAMAP-Rule:MF_01525}.
CC   -!- PATHWAY: Amine and polyamine metabolism; carnitine metabolism.
CC       {ECO:0000255|HAMAP-Rule:MF_01525}.
CC   -!- SIMILARITY: Belongs to the transferase hexapeptide repeat family.
CC       {ECO:0000255|HAMAP-Rule:MF_01525}.
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DR   EMBL; CP000970; ACB19069.1; -; Genomic_DNA.
DR   RefSeq; WP_000122898.1; NC_010498.1.
DR   AlphaFoldDB; B1LFW8; -.
DR   SMR; B1LFW8; -.
DR   EnsemblBacteria; ACB19069; ACB19069; EcSMS35_0036.
DR   KEGG; ecm:EcSMS35_0036; -.
DR   HOGENOM; CLU_064827_4_2_6; -.
DR   OMA; IRGDWGE; -.
DR   UniPathway; UPA00117; -.
DR   Proteomes; UP000007011; Chromosome.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009437; P:carnitine metabolic process; IEA:UniProtKB-UniPathway.
DR   HAMAP; MF_01525; CaiE; 1.
DR   InterPro; IPR023446; CaiE.
DR   InterPro; IPR001451; Hexapep.
DR   InterPro; IPR011004; Trimer_LpxA-like_sf.
DR   Pfam; PF00132; Hexapep; 2.
DR   SUPFAM; SSF51161; SSF51161; 1.
PE   3: Inferred from homology;
KW   Repeat; Transferase.
FT   CHAIN           1..196
FT                   /note="Carnitine operon protein CaiE"
FT                   /id="PRO_1000200923"
FT   REGION          173..196
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   196 AA;  21073 MW;  E3F0DFE2B86C1560 CRC64;
     MSYYAFEGLI PVVHPTAFVH PSAVLIGDVI VGAGVYIGPL ASLRGDYGRL LVQAGANIQD
     GCIMHGYCDT DTIVGENGHI GHGAILHGCV IGRDALVGMN SVIMDGAVIG EESIVAAMSF
     VKAGFRGEKR QLLMGTPARA VRSVSDDELH WKRLNTKEYQ DLVGRCHASL HETQPLRQME
     GNRPRLQGTT DVAPKR