VGAM_HAEIN
ID VGAM_HAEIN Reviewed; 169 AA.
AC O05070;
DT 15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1997, sequence version 1.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=Mu-like prophage FluMu host-nuclease inhibitor protein gam;
GN OrderedLocusNames=HI_1483;
OS Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=71421;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX PubMed=7542800; DOI=10.1126/science.7542800;
RA Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT Rd.";
RL Science 269:496-512(1995).
CC -!- FUNCTION: Protects linear double-stranded DNA of Mu genome from
CC exonuclease degradation. {ECO:0000250}.
CC -!- SIMILARITY: To phage Mu protein gam. {ECO:0000305}.
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DR EMBL; L42023; AAC23132.1; -; Genomic_DNA.
DR PIR; D64126; D64126.
DR RefSeq; NP_439634.1; NC_000907.1.
DR RefSeq; WP_005693500.1; NC_000907.1.
DR AlphaFoldDB; O05070; -.
DR SMR; O05070; -.
DR STRING; 71421.HI_1483; -.
DR EnsemblBacteria; AAC23132; AAC23132; HI_1483.
DR KEGG; hin:HI_1483; -.
DR PATRIC; fig|71421.8.peg.1550; -.
DR eggNOG; COG4396; Bacteria.
DR HOGENOM; CLU_130912_0_0_6; -.
DR OMA; TWCEAHR; -.
DR BioCyc; HINF71421:G1GJ1-1508-MON; -.
DR Proteomes; UP000000579; Chromosome.
DR GO; GO:0003690; F:double-stranded DNA binding; IEA:InterPro.
DR GO; GO:0042262; P:DNA protection; IEA:InterPro.
DR InterPro; IPR009951; Host-nuc_inhib_Gam.
DR Pfam; PF07352; Phage_Mu_Gam; 1.
PE 3: Inferred from homology;
KW DNA-binding; Reference proteome.
FT CHAIN 1..169
FT /note="Mu-like prophage FluMu host-nuclease inhibitor
FT protein gam"
FT /id="PRO_0000077640"
SQ SEQUENCE 169 AA; 19193 MW; EC142FE852098006 CRC64;
MATKVKSQAK LRFVSVEQVQ SAIKEIGDLS REHTRLATEM NDKIGATSEH YAPKLKALKE
EIEPLQKAVQ EYCEANRDEL TEFGKTKTAN FVTGEVQWRQ RPPSVAIRGA EAVMEFLQRM
GFDRFIRTRQ EINKEALLNE PEVAKGIAGV TIKQGLEDFV IKPFEQDAR