ID   VGE3_EHV2               Reviewed;         174 AA.
AC   Q66608;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   02-JUN-2021, entry version 62.
DE   RecName: Full=SUSHI domain-containing protein E3;
DE   Flags: Precursor;
GN   Name=E3;
OS   Equine herpesvirus 2 (strain 86/87) (EHV-2).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Gammaherpesvirinae; Percavirus.
OX   NCBI_TaxID=82831;
OH   NCBI_TaxID=9796; Equus caballus (Horse).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=7783207; DOI=10.1006/jmbi.1995.0314;
RA   Telford E.A.R., Watson M.S., Aird H.C., Perry J., Davison A.J.;
RT   "The DNA sequence of equine herpesvirus 2.";
RL   J. Mol. Biol. 249:520-528(1995).
CC   -!- SUBCELLULAR LOCATION: Host membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; U20824; AAC13790.1; -; Genomic_DNA.
DR   PIR; S55597; S55597.
DR   RefSeq; NP_042599.1; NC_001650.2.
DR   GeneID; 1461071; -.
DR   KEGG; vg:1461071; -.
DR   Proteomes; UP000007083; Genome.
DR   GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   CDD; cd00033; CCP; 1.
DR   InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR   InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR   SMART; SM00032; CCP; 1.
DR   SUPFAM; SSF57535; SSF57535; 1.
DR   PROSITE; PS50923; SUSHI; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Host membrane; Membrane; Reference proteome; Signal; Sushi;
KW   Transmembrane; Transmembrane helix.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..174
FT                   /note="SUSHI domain-containing protein E3"
FT                   /id="PRO_0000405991"
FT   TRANSMEM        145..165
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          35..97
FT                   /note="Sushi"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00302"
FT   REGION          108..133
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        108..130
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   DISULFID        37..78
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00302"
FT   DISULFID        64..95
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00302"
SQ   SEQUENCE   174 AA;  19348 MW;  F0043E44063CFB81 CRC64;
     MATEVQFACA LVVLLGCGYA GTPTPSKSTL IYNSQNCTTY PSIENGQSSL YYNGSWFIRY
     EFNCSSGYEL QGWPYTTCIF WPKNGTIWTN GPPSCVKLNI TTTLMPTSTS TTPVTTGTFP
     DPQNTTHPTH HTVKPTRRPI NLLRFGYTPW AIITLVVIIL LVVWIVNCCM GPMF