ID   VGE6_EHV2               Reviewed;         325 AA.
AC   Q66615;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   23-FEB-2022, entry version 55.
DE   RecName: Full=G-protein coupled receptor E6;
GN   Name=E6;
OS   Equine herpesvirus 2 (strain 86/87) (EHV-2).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Gammaherpesvirinae; Percavirus.
OX   NCBI_TaxID=82831;
OH   NCBI_TaxID=9796; Equus caballus (Horse).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=7783207; DOI=10.1006/jmbi.1995.0314;
RA   Telford E.A.R., Watson M.S., Aird H.C., Perry J., Davison A.J.;
RT   "The DNA sequence of equine herpesvirus 2.";
RL   J. Mol. Biol. 249:520-528(1995).
CC   -!- SUBCELLULAR LOCATION: Host membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000305}.
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DR   EMBL; U20824; AAC13798.1; -; Genomic_DNA.
DR   PIR; S55605; S55605.
DR   RefSeq; NP_042607.1; NC_001650.2.
DR   SMR; Q66615; -.
DR   GeneID; 1461034; -.
DR   KEGG; vg:1461034; -.
DR   Proteomes; UP000007083; Genome.
DR   GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
PE   3: Inferred from homology;
KW   G-protein coupled receptor; Host membrane; Membrane; Receptor;
KW   Reference proteome; Transducer; Transmembrane; Transmembrane helix.
FT   CHAIN           1..325
FT                   /note="G-protein coupled receptor E6"
FT                   /id="PRO_0000405983"
FT   TRANSMEM        45..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        71..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        106..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        145..165
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        198..218
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        233..253
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        274..294
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   325 AA;  35795 MW;  11D43B2CB5A1F99F CRC64;
     MEEMRHAGQI SRKLLFYFGS DNYNLSINDS MFRNCTLRAD RAAALFGTML EGVFLGIVLT
     MMGFFSVKTR FTPSSNIWLF AGCVAIALWL MTKMAQDYAP GPLKCIVTEN LALFCSLLGG
     ALNVGMCVDR CRAVYSRMAR GSMTPAAICT YIFWAVVGSL LVIAVNALEM SRNGLHMSEG
     LEGGCFQAAS PLAHRAKLVA KFLMYLVFVC IVSVGTALTL VKILNTNLNR KRAICVNVVL
     VTLPNTFIWL TAMTSAWREF SSYKMCPKIV TGNVFIYLSS VPMLVILFVY MFTGKNLKHT
     LRPQTRSYSS STGSASCFAH LAGKP