ID   VGE_BPG4                Reviewed;          96 AA.
AC   P03640;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   12-AUG-2020, entry version 71.
DE   RecName: Full=Lysis protein;
DE            Short=E protein;
DE   AltName: Full=GPE;
GN   Name=E;
OS   Escherichia phage G4 (Bacteriophage G4).
OC   Viruses; Monodnaviria; Sangervirae; Phixviricota; Malgrandaviricetes;
OC   Petitvirales; Microviridae; Bullavirinae; Gequatrovirus.
OX   NCBI_TaxID=10843;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=714153; DOI=10.1038/276236a0;
RA   Godson G.N., Barrell B.G., Staden R., Fiddes J.C.;
RT   "Nucleotide sequence of bacteriophage G4 DNA.";
RL   Nature 276:236-247(1978).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=160951; DOI=10.1016/0022-2836(79)90249-3;
RA   Fiddes J.C., Godson G.N.;
RT   "Evolution of the three overlapping gene systems in G4 and phi X174.";
RL   J. Mol. Biol. 133:19-43(1979).
CC   -!- FUNCTION: E protein is responsible for host cell lysis.
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DR   EMBL; V00657; CAA24017.1; -; Genomic_DNA.
DR   EMBL; M10637; AAA32327.1; -; Genomic_DNA.
DR   PIR; A04248; ZEBPG4.
DR   Proteomes; UP000002140; Genome.
DR   GO; GO:0004857; F:enzyme inhibitor activity; IEA:InterPro.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   GO; GO:0019054; P:modulation by virus of host cellular process; IEA:InterPro.
DR   InterPro; IPR007605; Micrvir_lysisE.
DR   Pfam; PF04517; Microvir_lysis; 1.
PE   4: Predicted;
KW   Cytolysis; Host cell lysis by virus; Reference proteome;
KW   Viral release from host cell.
FT   CHAIN           1..96
FT                   /note="Lysis protein"
FT                   /id="PRO_0000164883"
FT   CONFLICT        11..12
FT                   /note="AF -> LS (in Ref. 2; AAA32327)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   96 AA;  10531 MW;  9C7E96C2B3836BAD CRC64;
     MEHWTLSGIL AFLLLLSLFL PSLLITFIPL TSKPPVSSWK VLSLPKTSSM VLNAPLKPLN
     CSPSLFLFAP ETKILSVTLK QTSVNSYALK VSCKDL