ID   CAIE_SALTI              Reviewed;         198 AA.
AC   Q8Z9L6; Q83T88;
DT   07-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=Carnitine operon protein CaiE {ECO:0000255|HAMAP-Rule:MF_01525};
GN   Name=caiE {ECO:0000255|HAMAP-Rule:MF_01525};
GN   OrderedLocusNames=STY0079, t0070;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- FUNCTION: Overproduction of CaiE stimulates the activity of CaiB and
CC       CaiD. {ECO:0000255|HAMAP-Rule:MF_01525}.
CC   -!- PATHWAY: Amine and polyamine metabolism; carnitine metabolism.
CC       {ECO:0000255|HAMAP-Rule:MF_01525}.
CC   -!- SIMILARITY: Belongs to the transferase hexapeptide repeat family.
CC       {ECO:0000255|HAMAP-Rule:MF_01525}.
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DR   EMBL; AL513382; CAD01223.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO67803.1; -; Genomic_DNA.
DR   RefSeq; NP_454679.1; NC_003198.1.
DR   RefSeq; WP_000122865.1; NZ_PZMG01000007.1.
DR   AlphaFoldDB; Q8Z9L6; -.
DR   SMR; Q8Z9L6; -.
DR   STRING; 220341.16501352; -.
DR   EnsemblBacteria; AAO67803; AAO67803; t0070.
DR   KEGG; stt:t0070; -.
DR   KEGG; sty:STY0079; -.
DR   PATRIC; fig|220341.7.peg.78; -.
DR   eggNOG; COG0663; Bacteria.
DR   HOGENOM; CLU_064827_4_2_6; -.
DR   OMA; IRGDWGE; -.
DR   UniPathway; UPA00117; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009437; P:carnitine metabolic process; IEA:UniProtKB-UniPathway.
DR   HAMAP; MF_01525; CaiE; 1.
DR   InterPro; IPR023446; CaiE.
DR   InterPro; IPR001451; Hexapep.
DR   InterPro; IPR011004; Trimer_LpxA-like_sf.
DR   Pfam; PF00132; Hexapep; 2.
DR   SUPFAM; SSF51161; SSF51161; 1.
PE   3: Inferred from homology;
KW   Repeat; Transferase.
FT   CHAIN           1..198
FT                   /note="Carnitine operon protein CaiE"
FT                   /id="PRO_0000068725"
FT   REGION          179..198
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        150
FT                   /note="Y -> H (in Ref. 2; AAO67803)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   198 AA;  21358 MW;  29DE8B625E9BDCE9 CRC64;
     MSYYAFEGLI PVVHPDAFVH PSAVLIGDVI VGAGVYIGPL ASLRGDYGRL ILEAGSNLQD
     GCIMHGYCDT DTIVHENGHI GHGAILHGCV VGRDALVGMN SVIMDGAVIG EESIVAAMSF
     VKAGFQGEAR QLLVGSPARV LRQVTDQELY WKRLNTKEYQ DLAIRCRTGL SETKPLTQVE
     ENRPRLKGTT DVKPKSAQ