ID   VGLJ_CHV1               Reviewed;         117 AA.
AC   P36344;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Envelope glycoprotein J;
DE   Flags: Precursor;
GN   Name=gJ;
OS   Cercopithecine herpesvirus 1 (CeHV-1) (Simian herpes B virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Alphaherpesvirinae; Simplexvirus.
OX   NCBI_TaxID=10325;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
OH   NCBI_TaxID=9541; Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OH   NCBI_TaxID=90387; Macaca leonina (Northern pig-tailed macaque) (Macaca nemestrina leonina).
OH   NCBI_TaxID=9544; Macaca mulatta (Rhesus macaque).
OH   NCBI_TaxID=9545; Macaca nemestrina (Pig-tailed macaque).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1331298; DOI=10.1099/0022-1317-73-11-2963;
RA   Bennett A.M., Harrington L., Kelly D.C.;
RT   "Nucleotide sequence analysis of genes encoding glycoproteins D and J in
RT   simian herpes B virus.";
RL   J. Gen. Virol. 73:2963-2967(1992).
CC   -!- FUNCTION: Inhibits host cell apoptosis. Induces an increase in reactive
CC       oxygen species (ROS) in the host cell (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host Golgi apparatus membrane {ECO:0000305};
CC       Single-pass type I membrane protein {ECO:0000305}. Host endoplasmic
CC       reticulum membrane {ECO:0000305}; Single-pass type I membrane protein
CC       {ECO:0000305}. Host endosome membrane {ECO:0000305}; Single-pass type I
CC       membrane protein {ECO:0000305}. Note=Localizes to the endoplasmic
CC       reticulum, trans-Golgi network, and early endosomes. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the alphaherpesvirinae glycoprotein J family.
CC       {ECO:0000305}.
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DR   EMBL; S48101; AAB24128.1; -; Genomic_DNA.
DR   PIR; JQ1745; JQ1745.
DR   GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0044175; C:host cell endosome membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0044178; C:host cell Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR004913; Herpes_gJ.
DR   Pfam; PF03229; Alpha_GJ; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Host endoplasmic reticulum; Host endosome;
KW   Host Golgi apparatus; Host membrane; Membrane; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255"
FT   CHAIN           27..117
FT                   /note="Envelope glycoprotein J"
FT                   /id="PRO_0000115791"
FT   TOPO_DOM        27..73
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        74..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        95..117
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          26..64
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        36
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        46
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        58
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   117 AA;  11614 MW;  D16D4D2551ADFA2F CRC64;
     MRSLLFVVGA WVAAAVTHLT PNAALATGTT PTVGANSTAD PGTGANGTTV PAAGTPANST
     TAAETPAPFP PVDFALPVVI GGLCALTLAA MGAGALLHRC CRRAAARRRQ RAAYVYA