ID   CAIF_ECOLI              Reviewed;         131 AA.
AC   P0AE58; P75622; Q2MCH0; Q47081;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Transcriptional activatory protein CaiF;
GN   Name=caiF; OrderedLocusNames=b0034, JW0033;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=O44:K74;
RX   PubMed=8631699; DOI=10.1128/jb.178.5.1248-1257.1996;
RA   Eichler K., Buchet A., Lemke R., Kleber H.-P., Mandrand-Berthelot M.-A.;
RT   "Identification and characterization of the caiF gene encoding a potential
RT   transcriptional activator of carnitine metabolism in Escherichia coli.";
RL   J. Bacteriol. 178:1248-1257(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- FUNCTION: Potential transcriptional activator of carnitine metabolism.
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DR   EMBL; X80644; CAA56690.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC73145.2; -; Genomic_DNA.
DR   EMBL; AP009048; BAE76036.1; -; Genomic_DNA.
DR   RefSeq; NP_414576.4; NC_000913.3.
DR   RefSeq; WP_000333125.1; NZ_STEB01000010.1.
DR   AlphaFoldDB; P0AE58; -.
DR   SMR; P0AE58; -.
DR   BioGRID; 4263346; 6.
DR   BioGRID; 849196; 4.
DR   IntAct; P0AE58; 10.
DR   STRING; 511145.b0034; -.
DR   PaxDb; P0AE58; -.
DR   PRIDE; P0AE58; -.
DR   EnsemblBacteria; AAC73145; AAC73145; b0034.
DR   EnsemblBacteria; BAE76036; BAE76036; BAE76036.
DR   GeneID; 58460827; -.
DR   GeneID; 944795; -.
DR   KEGG; ecj:JW0033; -.
DR   KEGG; eco:b0034; -.
DR   PATRIC; fig|1411691.4.peg.2249; -.
DR   EchoBASE; EB3224; -.
DR   eggNOG; ENOG5030W1N; Bacteria.
DR   HOGENOM; CLU_144191_0_0_6; -.
DR   OMA; LIADWVM; -.
DR   PhylomeDB; P0AE58; -.
DR   BioCyc; EcoCyc:G6088-MON; -.
DR   PRO; PR:P0AE58; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IDA:EcoCyc.
DR   GO; GO:0009437; P:carnitine metabolic process; EXP:EcoliWiki.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:EcoCyc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IDA:EcoCyc.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR020357; Tscrpt_reg_CaiF/GrlA.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF07180; CaiF_GrlA; 1.
PE   4: Predicted;
KW   Activator; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..131
FT                   /note="Transcriptional activatory protein CaiF"
FT                   /id="PRO_0000089284"
SQ   SEQUENCE   131 AA;  15436 MW;  D2315E9DEBF976BD CRC64;
     MCEGYVEKPL YLLIAEWMMA ENRWVIAREI SIHFDIEHSK AVNTLTYILS EVTEISCEVK
     MIPNKLEGRG CQCQRLVKVV DIDEQIYARL RNNSREKLVG VRKTPRIPAV PLTELNREQK
     WQMMLSKSMR R