ID   VGRGA_DICD3             Reviewed;         617 AA.
AC   E0SAL0;
DT   16-OCT-2013, integrated into UniProtKB/Swiss-Prot.
DT   02-NOV-2010, sequence version 1.
DT   03-AUG-2022, entry version 53.
DE   RecName: Full=Putative type VI secretion system protein VgrGA;
GN   Name=vgrGA; OrderedLocusNames=Dda3937_01760;
OS   Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Dickeya.
OX   NCBI_TaxID=198628;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=3937;
RX   PubMed=21217001; DOI=10.1128/jb.01513-10;
RA   Glasner J.D., Yang C.H., Reverchon S., Hugouvieux-Cotte-Pattat N.,
RA   Condemine G., Bohin J.P., Van Gijsegem F., Yang S., Franza T., Expert D.,
RA   Plunkett G. III, San Francisco M.J., Charkowski A.O., Py B., Bell K.,
RA   Rauscher L., Rodriguez-Palenzuela P., Toussaint A., Holeva M.C., He S.Y.,
RA   Douet V., Boccara M., Blanco C., Toth I., Anderson B.D., Biehl B.S.,
RA   Mau B., Flynn S.M., Barras F., Lindeberg M., Birch P.R., Tsuyumu S.,
RA   Shi X., Hibbing M., Yap M.N., Carpentier M., Dassa E., Umehara M.,
RA   Kim J.F., Rusch M., Soni P., Mayhew G.F., Fouts D.E., Gill S.R.,
RA   Blattner F.R., Keen N.T., Perna N.T.;
RT   "Genome sequence of the plant-pathogenic bacterium Dickeya dadantii 3937.";
RL   J. Bacteriol. 193:2076-2077(2011).
RN   [2]
RP   POSSIBLE FUNCTION, AND DISRUPTION PHENOTYPE.
RC   STRAIN=3937;
RX   PubMed=23572593; DOI=10.1073/pnas.1300627110;
RA   Koskiniemi S., Lamoureux J.G., Nikolakakis K.C., t'Kint de Roodenbeke C.,
RA   Kaplan M.D., Low D.A., Hayes C.S.;
RT   "Rhs proteins from diverse bacteria mediate intercellular competition.";
RL   Proc. Natl. Acad. Sci. U.S.A. 110:7032-7037(2013).
CC   -!- FUNCTION: A Vgr protein that is probably part of a type VI secretion
CC       system (T6SS). May be required for export of proteins involved in Rhs-
CC       mediated cellular contact-dependent growth inhibition (CDI).
CC   -!- DISRUPTION PHENOTYPE: A double vgrGA-vgrGB deletion inhibits the
CC       ability of RhsB to inhibits cell growth. {ECO:0000269|PubMed:23572593}.
CC   -!- SIMILARITY: Belongs to the VgrG protein family. {ECO:0000305}.
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DR   EMBL; CP002038; ADM97068.1; -; Genomic_DNA.
DR   RefSeq; WP_013316544.1; NC_014500.1.
DR   AlphaFoldDB; E0SAL0; -.
DR   SMR; E0SAL0; -.
DR   STRING; 198628.Dda3937_01760; -.
DR   EnsemblBacteria; ADM97068; ADM97068; Dda3937_01760.
DR   GeneID; 9732269; -.
DR   KEGG; ddd:Dda3937_01760; -.
DR   PATRIC; fig|198628.6.peg.861; -.
DR   eggNOG; COG3501; Bacteria.
DR   HOGENOM; CLU_004121_7_2_6; -.
DR   OMA; VWTHRYE; -.
DR   OrthoDB; 1880900at2; -.
DR   BioCyc; DDAD198628:DDA3937_RS04105-MON; -.
DR   Proteomes; UP000006859; Chromosome.
DR   Gene3D; 2.40.50.230; -; 1.
DR   InterPro; IPR006531; Gp5/Vgr_OB.
DR   InterPro; IPR017847; T6SS_RhsGE_Vgr_subset.
DR   InterPro; IPR006533; T6SS_Vgr_RhsGE.
DR   InterPro; IPR037026; Vgr_OB-fold_dom_sf.
DR   Pfam; PF04717; Phage_base_V; 1.
DR   TIGRFAMs; TIGR01646; vgr_GE; 1.
DR   TIGRFAMs; TIGR03361; VI_Rhs_Vgr; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..617
FT                   /note="Putative type VI secretion system protein VgrGA"
FT                   /id="PRO_0000423982"
FT   REGION          325..344
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          449..469
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   617 AA;  67748 MW;  12049FF8C6030D20 CRC64;
     MANSTGLQFT VKVGALPDTT FAVVDFELSE ALNQPFALSL NLASSLPGID FGAVLDQPCE
     LLVWYEGELQ RRVSGIVSRF AQGDTGFRRT RYQAEVRPAL WRLGLRTNAR IFQTQKPDAI
     IGTLLEEAGI TDFAFALRHE HAVREYCVQY RESDLAFINR LAAEEGLFYF HEFEAGKHRV
     VFADDAGALT KGPELFFNLA TQGLSEGAYV RRFRYAEAVS TAEVALKDYS FKTPAYGLLH
     NKMSSELDHQ RETYQHFDYP GRFKQDPSGK AFTGYRLDAL RAGAMTGEGE SNAAELMPGS
     SFTLTEHPNP AFNLAWQVVA VTHSGQQPQA LEEESGGEPT TLSNSFEVVK GTTTWRAAMP
     YKPMVDGPQI ATVVGPAGEE IYCDEFGRIK LQFPWDRYGA SDDQSSCWVR VSQGWAGGQY
     GLIAIPRIGH EVVVSFLEGD PDQPIVTGRT FHATNPSPYP LPASKTRTSL RTSTHKGAGF
     NELRFEDQAG QEEVFIHAQK DMNTVVLNNR STSVNASHTE NVGGDQTVVV QHNQTVSVKE
     NQVTEIQGEQ TVAVTQNRNT TVNDNESLQV KNNIAIQSQS GDILIATAGG FIAIDKDGNI
     SITGKGLVLN GTRIDLN