ID   VGRGB_DICD3             Reviewed;         617 AA.
AC   E0SIS4;
DT   16-OCT-2013, integrated into UniProtKB/Swiss-Prot.
DT   02-NOV-2010, sequence version 1.
DT   03-AUG-2022, entry version 52.
DE   RecName: Full=Putative type VI secretion system protein VgrGB;
GN   Name=vgrGB; OrderedLocusNames=Dda3937_02771;
OS   Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Dickeya.
OX   NCBI_TaxID=198628;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=3937;
RX   PubMed=21217001; DOI=10.1128/jb.01513-10;
RA   Glasner J.D., Yang C.H., Reverchon S., Hugouvieux-Cotte-Pattat N.,
RA   Condemine G., Bohin J.P., Van Gijsegem F., Yang S., Franza T., Expert D.,
RA   Plunkett G. III, San Francisco M.J., Charkowski A.O., Py B., Bell K.,
RA   Rauscher L., Rodriguez-Palenzuela P., Toussaint A., Holeva M.C., He S.Y.,
RA   Douet V., Boccara M., Blanco C., Toth I., Anderson B.D., Biehl B.S.,
RA   Mau B., Flynn S.M., Barras F., Lindeberg M., Birch P.R., Tsuyumu S.,
RA   Shi X., Hibbing M., Yap M.N., Carpentier M., Dassa E., Umehara M.,
RA   Kim J.F., Rusch M., Soni P., Mayhew G.F., Fouts D.E., Gill S.R.,
RA   Blattner F.R., Keen N.T., Perna N.T.;
RT   "Genome sequence of the plant-pathogenic bacterium Dickeya dadantii 3937.";
RL   J. Bacteriol. 193:2076-2077(2011).
RN   [2]
RP   POSSIBLE FUNCTION, AND DISRUPTION PHENOTYPE.
RC   STRAIN=3937;
RX   PubMed=23572593; DOI=10.1073/pnas.1300627110;
RA   Koskiniemi S., Lamoureux J.G., Nikolakakis K.C., t'Kint de Roodenbeke C.,
RA   Kaplan M.D., Low D.A., Hayes C.S.;
RT   "Rhs proteins from diverse bacteria mediate intercellular competition.";
RL   Proc. Natl. Acad. Sci. U.S.A. 110:7032-7037(2013).
CC   -!- FUNCTION: A Vgr protein that is probably part of a type VI secretion
CC       system (T6SS). May be required for export of proteins involved in Rhs-
CC       mediated cellular contact-dependent growth inhibition (CDI).
CC   -!- DISRUPTION PHENOTYPE: A double vgrGA-vgrGB deletion inhibits the
CC       ability of RhsB to inhibits cell growth. VgrGB alone restores RhsB-
CC       mediated cell growth. {ECO:0000269|PubMed:23572593}.
CC   -!- SIMILARITY: Belongs to the VgrG protein family. {ECO:0000305}.
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DR   EMBL; CP002038; ADM99133.1; -; Genomic_DNA.
DR   RefSeq; WP_013318571.1; NC_014500.1.
DR   AlphaFoldDB; E0SIS4; -.
DR   SMR; E0SIS4; -.
DR   STRING; 198628.Dda3937_02771; -.
DR   EnsemblBacteria; ADM99133; ADM99133; Dda3937_02771.
DR   GeneID; 9734380; -.
DR   KEGG; ddd:Dda3937_02771; -.
DR   PATRIC; fig|198628.6.peg.2916; -.
DR   eggNOG; COG3501; Bacteria.
DR   HOGENOM; CLU_004121_8_2_6; -.
DR   OMA; NTHTIES; -.
DR   OrthoDB; 1880900at2; -.
DR   BioCyc; DDAD198628:DDA3937_RS13765-MON; -.
DR   Proteomes; UP000006859; Chromosome.
DR   Gene3D; 2.40.50.230; -; 1.
DR   InterPro; IPR006531; Gp5/Vgr_OB.
DR   InterPro; IPR017847; T6SS_RhsGE_Vgr_subset.
DR   InterPro; IPR006533; T6SS_Vgr_RhsGE.
DR   InterPro; IPR037026; Vgr_OB-fold_dom_sf.
DR   Pfam; PF04717; Phage_base_V; 1.
DR   TIGRFAMs; TIGR01646; vgr_GE; 1.
DR   TIGRFAMs; TIGR03361; VI_Rhs_Vgr; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..617
FT                   /note="Putative type VI secretion system protein VgrGB"
FT                   /id="PRO_0000423983"
FT   REGION          449..469
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   617 AA;  67692 MW;  897EE3CEDEC1F721 CRC64;
     MANSTGLQFT VKVGALPDTT FAVVDFELSE ALNQPFALSL NLASSQPGID FGAVLDQPCE
     LLVWYEGELQ RRVSGIVSRF AQGDTGFRRT RYQAEVRPAL WRLGLRTNAR IFQTQKPDAI
     ISTLLEEAGI TDYAFALRHD HAVREYCVQY RESDLAFINR LAAEEGLFYF HEFEAGKHRV
     VFADDAGALA KGPELFFNLA TQGLSEGAYV RRFRYAEAVS TAEVALKDYS FKTPAYGLLH
     NKMSSELAHQ RESYQHFDYP GRFKQDPSGK AFTGYRLDAL RAGAMTGNGE SNAAELRPGS
     SFTLTEHPNP AFNLAWQVVA VAHSGQQPQA LEEESGGEPT TLSNSFEVVK ATTTWRAALP
     YKPMVDGPQI ATVVGPAGEE IYCDEFGRVK LQFPWDRYGA SDDQSSCWVR VSQGWAGGQY
     GLIAIPRIGH EVVVSFLEGD PDQPIVTGRT FHATNPSPYP LPASKTRTSL RTSTHKGAGF
     NELRFEDQAG QEEVFIHAQK DMNTVVLNNR STSVNASHTE NVGGDQTVVV QHNQTVSVKE
     NQVTEIQGEQ TVAVTKNRHT TVDDNESLQV KKNIAIQSQS GDVLIATAGG FIAIDKDGNI
     SITGKGLVLN GTRIDLN