ID   VHCG_METVO              Reviewed;         306 AA.
AC   Q00406;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=F420-non-reducing hydrogenase vhc subunit G;
DE            EC=1.12.99.-;
GN   Name=vhcG;
OS   Methanococcus voltae.
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanococcaceae; Methanococcus.
OX   NCBI_TaxID=2188;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 33273 / DSM 1537 / NBRC 100457 / OCM 70 / PS;
RX   PubMed=1603063; DOI=10.1007/bf00587582;
RA   Halboth S., Klein A.;
RT   "Methanococcus voltae harbors four gene clusters potentially encoding two
RT   [NiFe] and two [NiFeSe] hydrogenases, each of the cofactor F420-reducing or
RT   F420-non-reducing types.";
RL   Mol. Gen. Genet. 233:217-224(1992).
RN   [2]
RP   TRANSCRIPTIONAL REGULATION.
RC   STRAIN=ATCC 33273 / DSM 1537 / NBRC 100457 / OCM 70 / PS;
RX   PubMed=8121392; DOI=10.1007/bf00281785;
RA   Berghoefer Y., Agha-Amiri K., Klein A.;
RT   "Selenium is involved in the negative regulation of the expression of
RT   selenium-free [NiFe] hydrogenases in Methanococcus voltae.";
RL   Mol. Gen. Genet. 242:369-373(1994).
CC   -!- SUBUNIT: The F420-non-reducing hydrogenase vhc is composed of three
CC       subunits; VhcA, VhcD and VhcG. {ECO:0000250}.
CC   -!- INDUCTION: By selenium deprivation. {ECO:0000269|PubMed:8121392}.
CC   -!- SIMILARITY: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit
CC       family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X61203; CAA43505.1; -; Genomic_DNA.
DR   PIR; S32834; S32834.
DR   AlphaFoldDB; Q00406; -.
DR   SMR; Q00406; -.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.700; -; 1.
DR   InterPro; IPR006137; NADH_UbQ_OxRdtase-like_20kDa.
DR   InterPro; IPR037024; NiFe_Hase_small_N_sf.
DR   Pfam; PF01058; Oxidored_q6; 1.
PE   2: Evidence at transcript level;
KW   Oxidoreductase.
FT   CHAIN           1..306
FT                   /note="F420-non-reducing hydrogenase vhc subunit G"
FT                   /id="PRO_0000204360"
SQ   SEQUENCE   306 AA;  33636 MW;  2A88AC3EAE194D8B CRC64;
     MGKIATTCRG CCSGCHISLI DLHEDLLDIL EQVELIHSPV LMDVREIPDD IDVALIEGGV
     RSGENLHIAR EMREEAKVVI AFGTCAVYGG IPGMGNLYSN EELLEKAYKT TITTKNDEGI
     IPSEEVPALT SRVTPLSQVI DVDYIFQDAP PKPELIASVL TALLEEKEPE LSNKNMCEVC
     PREKSSEGVV VGELKRNYEG EIDPKKCLLE QGYVCMGVAT RASCRCFCAL VRHVPCTGCY
     GPTDKVVDQG AKMISALASD YKVDDDKEMN PKELPNKIID KVGSFYKFTL PSALIPVKND
     RNKKII