ID   VHUD_METKA              Reviewed;         132 AA.
AC   Q8TXN5;
DT   19-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   26-FEB-2008, sequence version 3.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=F420-non-reducing hydrogenase vhu iron-sulfur subunit D;
DE            EC=1.12.99.-;
GN   Name=vhuD; OrderedLocusNames=MK0627;
OS   Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938).
OC   Archaea; Euryarchaeota; Methanopyri; Methanopyrales; Methanopyraceae;
OC   Methanopyrus.
OX   NCBI_TaxID=190192;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AV19 / DSM 6324 / JCM 9639 / NBRC 100938;
RX   PubMed=11930014; DOI=10.1073/pnas.032671499;
RA   Slesarev A.I., Mezhevaya K.V., Makarova K.S., Polushin N.N.,
RA   Shcherbinina O.V., Shakhova V.V., Belova G.I., Aravind L., Natale D.A.,
RA   Rogozin I.B., Tatusov R.L., Wolf Y.I., Stetter K.O., Malykh A.G.,
RA   Koonin E.V., Kozyavkin S.A.;
RT   "The complete genome of hyperthermophile Methanopyrus kandleri AV19 and
RT   monophyly of archaeal methanogens.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:4644-4649(2002).
CC   -!- COFACTOR:
CC       Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:190135; Evidence={ECO:0000250};
CC       Note=Binds 1 [2Fe-2S] cluster. {ECO:0000250};
CC   -!- SUBUNIT: The F420-non-reducing hydrogenase vhu is composed of four
CC       subunits; VhuA, VhuD, VhuG and VhuU. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MvhD/VhuD family. {ECO:0000305}.
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DR   EMBL; AE009439; AAM01842.1; -; Genomic_DNA.
DR   STRING; 190192.MK0627; -.
DR   KEGG; mka:MK0627; -.
DR   HOGENOM; CLU_095272_2_0_2; -.
DR   OMA; XGYGAAD; -.
DR   Proteomes; UP000001826; Chromosome.
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR003813; MvhD/FlpD.
DR   Pfam; PF02662; FlpD; 1.
PE   3: Inferred from homology;
KW   2Fe-2S; Electron transport; Iron; Iron-sulfur; Metal-binding;
KW   Oxidoreductase; Reference proteome; Selenocysteine; Transport.
FT   CHAIN           1..132
FT                   /note="F420-non-reducing hydrogenase vhu iron-sulfur
FT                   subunit D"
FT                   /id="PRO_0000249590"
FT   NON_STD         15
FT                   /note="Selenocysteine"
FT                   /evidence="ECO:0000250"
FT   NON_STD         66
FT                   /note="Selenocysteine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   132 AA;  14445 MW;  6047EAA8B011A07A CRC64;
     MSEESVVVAF CCYEUGYGAA DLAGTGRAQY PSSVRIVRVP CTGRVGIEHI LTALAKGAWT
     VFVAGUKKGE CSYEDGNLKC ERRVQAAKKL LEELGIEPER VEIYFMSSAE ADKFVAAVKE
     MHERAKELGP LA