ID   VIF_FIVPE               Reviewed;         251 AA.
AC   P16089;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 2.
DT   29-SEP-2021, entry version 60.
DE   RecName: Full=Virion infectivity factor;
GN   Name=vif;
OS   Feline immunodeficiency virus (isolate Petaluma) (FIV).
OC   Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC   Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus.
OX   NCBI_TaxID=11674;
OH   NCBI_TaxID=9681; Felidae (cat family).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RC   STRAIN=Clone 34TF10;
RX   PubMed=2762293; DOI=10.1073/pnas.86.15.5743;
RA   Talbott R.L., Sparger E.E., Lovelace K.M., Fitch W.M., Pedersen N.C.,
RA   Luciw P.A., Elder J.H.;
RT   "Nucleotide sequence and genomic organization of feline immunodeficiency
RT   virus.";
RL   Proc. Natl. Acad. Sci. U.S.A. 86:5743-5747(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RC   STRAIN=Clone FIV-14;
RX   PubMed=2813380; DOI=10.1073/pnas.86.20.8088;
RA   Olmsted R.A., Hirsch V.M., Purcell R.H., Johnson P.R.;
RT   "Nucleotide sequence analysis of feline immunodeficiency virus: genome
RT   organization and relationship to other lentiviruses.";
RL   Proc. Natl. Acad. Sci. U.S.A. 86:8088-8092(1989).
CC   -!- FUNCTION: Determines virus infectivity.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000250}. Virion
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the feline lentivirus group Vif protein family.
CC       {ECO:0000305}.
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DR   EMBL; M25381; AAB59938.1; -; Genomic_RNA.
DR   PIR; C33543; ASLJFP.
DR   RefSeq; NP_040974.1; NC_001482.1.
DR   SMR; P16089; -.
DR   GeneID; 1724709; -.
DR   KEGG; vg:1724709; -.
DR   Proteomes; UP000242267; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0019058; P:viral life cycle; IEA:InterPro.
DR   InterPro; IPR008668; Vir_infectivity_fact_Lentivir.
DR   Pfam; PF05851; Lentivirus_VIF; 1.
PE   3: Inferred from homology;
KW   Host cytoplasm; Reference proteome; Virion.
FT   CHAIN           1..251
FT                   /note="Virion infectivity factor"
FT                   /id="PRO_0000085500"
SQ   SEQUENCE   251 AA;  29138 MW;  F0554CA47F342855 CRC64;
     MSEEDWQVSR RLFAVLQGGV NSAMLYISRL PPDEREKYKK DFKKRLFDTE TGFIKRLRKA
     EGIKWSFHTR DYYIGYVREM VAGSTTSLSL RMYIYISNPL WHSQYRPGLK NFNKEWPFVN
     MWIKTGFMWD DIEKQNICIG GEVSPGWGPG MVGIAIKAFS CGERKIEATP VMIIRGEIDP
     KKWCGDCWNL MCLRNSPPKT LQRLAMLACG VPAKKWRGCC NQRFVSPYRT PADLEVIQSK
     PSWNLLWSGE L