ID   VIF_FIVT2               Reviewed;         251 AA.
AC   P31823;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   29-SEP-2021, entry version 48.
DE   RecName: Full=Virion infectivity factor;
GN   Name=vif;
OS   Feline immunodeficiency virus (isolate TM2) (FIV).
OC   Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC   Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus.
OX   NCBI_TaxID=31676;
OH   NCBI_TaxID=9681; Felidae (cat family).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=1649349; DOI=10.1128/jvi.65.8.4539-4542.1991;
RA   Kiyomasu T., Miyazawa T., Furuya T., Shibata R., Sakai H., Sakuragi J.I.,
RA   Fukasawa M., Maki N., Hasegawa A., Mikami T., Adachi A.;
RT   "Identification of feline immunodeficiency virus rev gene activity.";
RL   J. Virol. 65:4539-4542(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=1312825; DOI=10.1007/bf01317136;
RA   Maki N., Miyazawa T., Fukasawa M., Hasegawa A., Hayami M., Miki K.,
RA   Mikami T.;
RT   "Molecular characterization and heterogeneity of feline immunodeficiency
RT   virus isolates.";
RL   Arch. Virol. 123:29-45(1992).
CC   -!- FUNCTION: Determines virus infectivity.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000250}. Virion
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the feline lentivirus group Vif protein family.
CC       {ECO:0000305}.
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DR   EMBL; M59418; AAA43073.1; -; Genomic_RNA.
DR   PIR; C45557; C45557.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0019058; P:viral life cycle; IEA:InterPro.
DR   InterPro; IPR008668; Vir_infectivity_fact_Lentivir.
DR   Pfam; PF05851; Lentivirus_VIF; 1.
PE   3: Inferred from homology;
KW   Host cytoplasm; Virion.
FT   CHAIN           1..251
FT                   /note="Virion infectivity factor"
FT                   /id="PRO_0000085502"
SQ   SEQUENCE   251 AA;  29196 MW;  391388524CF1C36D CRC64;
     MSDEDWQVSR RLFAVLQGGV YSAMLYISSL PEMEQDKCKR SFKKRLSEKE TGFIFRLRKA
     EGIRWSFHTR DYYIGYVREM VAGSSLPDSL RLYVYISNPL WHQSYRPGLT NFNTEWPFVN
     MWIKTGFMWD DIESQNICKG GEISHGWGPG MVGIVIKAFS CGERKIKITP VMIIRGEIDP
     TEWCGDCWNL MCLKYSPPNT LQRLAMLACG KEAKEWRGCC NQRFVSPFRT PCDLEVVQNK
     PKRNLLWTGE L