ID   VIGLN_CHICK             Reviewed;        1270 AA.
AC   P81021;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Vigilin;
GN   Name=HDLBP; Synonyms=VGL;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Embryonic sternal cartilage;
RX   PubMed=1606952; DOI=10.1111/j.1432-1033.1992.tb16967.x;
RA   Schmidt C., Henkel B., Poeschl E., Zorbas H., Purschke W.G., Gloe T.R.,
RA   Mueller P.K.;
RT   "Complete cDNA sequence of chicken vigilin, a novel protein with amplified
RT   and evolutionary conserved domains.";
RL   Eur. J. Biochem. 206:625-634(1992).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
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DR   EMBL; X65292; CAA46387.1; -; mRNA.
DR   PIR; S23464; S23464.
DR   AlphaFoldDB; P81021; -.
DR   SMR; P81021; -.
DR   STRING; 9031.ENSGALP00000009341; -.
DR   PaxDb; P81021; -.
DR   PRIDE; P81021; -.
DR   VEuPathDB; HostDB:geneid_395984; -.
DR   eggNOG; KOG2208; Eukaryota.
DR   InParanoid; P81021; -.
DR   PhylomeDB; P81021; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0005844; C:polysome; IBA:GO_Central.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   Gene3D; 3.30.1370.10; -; 13.
DR   InterPro; IPR004087; KH_dom.
DR   InterPro; IPR004088; KH_dom_type_1.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   Pfam; PF00013; KH_1; 14.
DR   SMART; SM00322; KH; 14.
DR   SUPFAM; SSF54791; SSF54791; 14.
DR   PROSITE; PS50084; KH_TYPE_1; 14.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Reference proteome; Repeat; RNA-binding.
FT   CHAIN           1..1270
FT                   /note="Vigilin"
FT                   /id="PRO_0000050134"
FT   DOMAIN          150..188
FT                   /note="KH 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00117"
FT   DOMAIN          219..260
FT                   /note="KH 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00117"
FT   DOMAIN          291..333
FT                   /note="KH 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00117"
FT   DOMAIN          360..402
FT                   /note="KH 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00117"
FT   DOMAIN          431..473
FT                   /note="KH 5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00117"
FT   DOMAIN          504..545
FT                   /note="KH 6"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00117"
FT   DOMAIN          577..619
FT                   /note="KH 7"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00117"
FT   DOMAIN          651..693
FT                   /note="KH 8"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00117"
FT   DOMAIN          724..766
FT                   /note="KH 9"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00117"
FT   DOMAIN          798..840
FT                   /note="KH 10"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00117"
FT   DOMAIN          872..913
FT                   /note="KH 11"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00117"
FT   DOMAIN          970..1012
FT                   /note="KH 12"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00117"
FT   DOMAIN          1051..1093
FT                   /note="KH 13"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00117"
FT   DOMAIN          1126..1168
FT                   /note="KH 14"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00117"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          28..47
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          911..947
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1217..1270
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        929..947
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1270 AA;  142221 MW;  0A8844F91F9B8619 CRC64;
     MSSVAVLTQE SFAEHRSGLT QQQVKVTALN SEEENDPPTY KEAFPPLPEK APCLEAAQEP
     SGPWSKIRPI KASVITQVFH VPLEERKYKD MNQFGEGEQA KICLDIMQKT GAHLELSLAK
     DQGLSIMVSG KLEAVMKARK EIVARLQTQA SATVAIPKEH HRFVIGKNGE KLQDLELKTA
     TKIQIPRPDD PSNQIKITGT KEGIEKARHE ILLISAEQDK RAVERLDVEK VYHPFIAGPY
     NKLVSELMQD TGTRINIPPP SVNKTEIVFT GEKEQLAQAV ARVKKIYEEK KKKTTTIAVE
     VKKSQHKYVI GRKGNSLQEI LEKTGVSVEI PPTDSSSETV ILRGEPEKLG QALTEVYAKA
     NSFTVSSVSA PSWLHRFIIG LFGQNLAKIT QQMPKIHIEF TEGEDKITSE GPTEDVNVAQ
     EQIEVMVKDL INRTDYAEIN VDHKFHRHLI GKNGANINRI KDLYKVSVRI PPDNEKSNLI
     RIEGDPQGVQ QAKKELLELA SRMENERTKD LIIEQKFHRT IIGQKGERIR EIREKFPEVI
     INFPDPAHKS DIVQLRGPKN EVEKCTKYMQ KMVADLVENS FSISVPIFKQ FHKNIIGKGG
     ANIKKIREES NTKIDLPGRE QATQRQLLSQ GREQTVKLLR HRILAIQKEL ANITEVEVSI
     PSKLHNSLIG AKGRFIRSIM EECGGVHIHF PTEGSGSATV TIRAQPRTWR KPRSSCCTWA
     EEKQTKSYTV DLRAKPEYHK FLIGKGGGNI RKVRDNTGAR IIFPTSEDKD QELITIMGTE
     EAVKEAQKEL EALIKNLDNV VEDSMVVDPK HHRHFVIRRG QVLREIADEY GGVMVRLPTV
     SGTQSDKVTL KGAKDCVEAA KKRIQEIIED LEAQVTIECT IPQKFHRSIM GPKGSRIQQI
     TRDYGVQIKF PDREENPAPV AEPALQENGE EGGEGKDGKD ADPSSPRKCD IIIISGRREK
     CEAAKEALQA LVPVTIEVEV PFDLHRYIIG QKGSGIRKMM DEFEVNIQVP APELQSSDII
     TITGLAANLD RAKAGLLERV KELQAEQEDR ALRSFKLTVT VDPKYHPKII GRKGAVITQI
     RTEHEVNIQF PDKDDESQAQ DQITITGYEK NAEAARDAIM KIVGELEQMV SEDVTLDHRV
     HARIIGARGK AIRKIMDEFK VDIRFPQSGA PDPNCVTVTG LPENVEEAID HILNLEEEYL
     ADVVDNEAMQ VYMKPSSHEE SKVPSKGFVV RDAPCGTVNN EKAPDMSSSE DFPSFGAQVA
     PKTLPWGPKR