ID   VIMP1_USTMA             Reviewed;         142 AA.
AC   A0A0D1E6R6;
DT   23-FEB-2022, integrated into UniProtKB/Swiss-Prot.
DT   29-APR-2015, sequence version 1.
DT   23-FEB-2022, entry version 16.
DE   RecName: Full=Virulence-associated membrane protein 1 {ECO:0000303|PubMed:34093627};
DE            Short=VMP1 {ECO:0000303|PubMed:34093627};
DE   Flags: Precursor;
GN   Name=VMP1 {ECO:0000303|PubMed:34093627};
GN   ORFNames=UMAG_00032 {ECO:0000312|EMBL:KIS71589.1};
OS   Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX   NCBI_TaxID=237631 {ECO:0000312|Proteomes:UP000000561};
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=521 / FGSC 9021 {ECO:0000312|Proteomes:UP000000561};
RX   PubMed=17080091; DOI=10.1038/nature05248;
RA   Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., Saville B.J.,
RA   Banuett F., Kronstad J.W., Gold S.E., Mueller O., Perlin M.H.,
RA   Woesten H.A.B., de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G.,
RA   Snetselaar K., McCann M., Perez-Martin J., Feldbruegge M., Basse C.W.,
RA   Steinberg G., Ibeas J.I., Holloman W., Guzman P., Farman M.L.,
RA   Stajich J.E., Sentandreu R., Gonzalez-Prieto J.M., Kennell J.C., Molina L.,
RA   Schirawski J., Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N.,
RA   Scherer M., Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B.,
RA   Meng S., Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA   Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA   Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA   Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA   Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., Muensterkoetter M.,
RA   Haase D., Oesterheld M., Mewes H.-W., Mauceli E.W., DeCaprio D., Wade C.M.,
RA   Butler J., Young S.K., Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E.,
RA   Birren B.W.;
RT   "Insights from the genome of the biotrophic fungal plant pathogen Ustilago
RT   maydis.";
RL   Nature 444:97-101(2006).
RN   [2] {ECO:0000312|Proteomes:UP000000561}
RP   GENOME REANNOTATION.
RC   STRAIN=521 / FGSC 9021 {ECO:0000312|Proteomes:UP000000561};
RA   Gueldener U., Muensterkoetter M., Walter M.C., Mannhaupt G., Kahmann R.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000305}
RP   FUNCTION, SUBUNIT, SUBCELLULAR LOCATION, AND DISRUPTION PHENOTYPE.
RC   STRAIN=SG200 {ECO:0000303|PubMed:34093627};
RX   PubMed=34093627; DOI=10.3389/fpls.2021.669835;
RA   Weiland P., Altegoer F.;
RT   "Identification and Characterization of Two Transmembrane Proteins Required
RT   for Virulence of Ustilago maydis.";
RL   Front. Plant Sci. 12:669835-669835(2021).
CC   -!- FUNCTION: During infection, may play a role in establishing and
CC       maintaining biotrophy; the formation of a tight interaction zone
CC       between the host and the pathogen. {ECO:0000269|PubMed:34093627}.
CC   -!- SUBUNIT: Monomer. {ECO:0000305|PubMed:34093627}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305|PubMed:34093627}; Single-
CC       pass membrane protein {ECO:0000255}.
CC   -!- DISRUPTION PHENOTYPE: Decreases virulence in Zea mays.
CC       {ECO:0000269|PubMed:34093627}.
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DR   EMBL; CM003140; KIS71589.1; -; Genomic_DNA.
DR   RefSeq; XP_011386009.1; XM_011387707.1.
DR   EnsemblFungi; KIS71589; KIS71589; UMAG_00032.
DR   GeneID; 23561443; -.
DR   KEGG; uma:UMAG_00032; -.
DR   VEuPathDB; FungiDB:UMAG_00032; -.
DR   eggNOG; ENOG502R2XU; Eukaryota.
DR   OrthoDB; 1609753at2759; -.
DR   Proteomes; UP000000561; Chromosome 1.
DR   GO; GO:0016021; C:integral component of membrane; IDA:UniProtKB.
DR   GO; GO:0051701; P:biological process involved in interaction with host; IMP:UniProtKB.
PE   1: Evidence at protein level;
KW   Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix;
KW   Virulence.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..142
FT                   /note="Virulence-associated membrane protein 1"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_5002229662"
FT   TRANSMEM        59..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   142 AA;  15458 MW;  ADA12EE1B38AC6DC CRC64;
     MRGILVALTA ALIFCSLTPA QPVLHIQETN RAKNRANRKL VARQPEYKAV ETLEKNVNIA
     IAVGTALVTL VSAGVGGMLL SDHLACKSVA KQEEIMQKSW DSMHPDGFTP AGDQMRPVSF
     DCSTQERGLK PLQSYTNGAE MY