ID   VINT_BPL2               Reviewed;         289 AA.
AC   P42540;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   02-DEC-2020, entry version 84.
DE   RecName: Full=Probable integrase/recombinase;
DE            EC=2.7.7.- {ECO:0000250|UniProtKB:P36932};
DE            EC=3.1.-.- {ECO:0000250|UniProtKB:P36932};
DE   AltName: Full=ORF5;
OS   Acholeplasma phage L2 (Bacteriophage L2).
OC   Viruses; Plasmaviridae; Plasmavirus.
OX   NCBI_TaxID=46014;
OH   NCBI_TaxID=2093; Mycoplasma.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=8163159; DOI=10.1016/0378-1119(94)90120-1;
RA   Maniloff J., Kampo G.J., Dascher C.C.;
RT   "Sequence analysis of a unique temperature phage: mycoplasma virus L2.";
RL   Gene 141:1-8(1994).
CC   -!- FUNCTION: May function as an integrase.
CC   -!- SIMILARITY: Belongs to the 'phage' integrase family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; L13696; AAA87961.1; -; Genomic_DNA.
DR   RefSeq; NP_040813.1; NC_001447.1.
DR   SMR; P42540; -.
DR   GeneID; 1261006; -.
DR   KEGG; vg:1261006; -.
DR   Proteomes; UP000001573; Genome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0075713; P:establishment of integrated proviral latency; IEA:UniProtKB-KW.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   GO; GO:0044826; P:viral genome integration into host DNA; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.443.10; -; 1.
DR   InterPro; IPR044068; CB.
DR   InterPro; IPR011010; DNA_brk_join_enz.
DR   InterPro; IPR013762; Integrase-like_cat_sf.
DR   InterPro; IPR002104; Integrase_catalytic.
DR   Pfam; PF00589; Phage_integrase; 1.
DR   SUPFAM; SSF56349; SSF56349; 1.
DR   PROSITE; PS51900; CB; 1.
DR   PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE   3: Inferred from homology;
KW   DNA integration; DNA recombination; DNA-binding; Hydrolase;
KW   Reference proteome; Transferase; Viral genome integration;
KW   Virus entry into host cell.
FT   CHAIN           1..289
FT                   /note="Probable integrase/recombinase"
FT                   /id="PRO_0000197502"
FT   DOMAIN          1..86
FT                   /note="Core-binding (CB)"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01248"
FT   DOMAIN          102..281
FT                   /note="Tyr recombinase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        144
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        169
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        233
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        236
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        259
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        268
FT                   /note="O-(3'-phospho-DNA)-tyrosine intermediate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
SQ   SEQUENCE   289 AA;  34871 MW;  B5B806C823A75BD3 CRC64;
     MNIEKALMNY YELTLASYED STNRYHYRIV QHLIKGLKYI KVKKLEKVDI TIGYKLIDYL
     KNHTHNGNNS IKKIINYLRK VMQHYRITTS IIDLPHLPND TKPFERFYHD DLELIMTYTK
     NLNSSKNSIT YKSFIRLLLD SGLRVSEALN IKISDMDFKN KVIRVLSSKT RKQRYAPFSS
     FSLKYIKELI EVNPKRDYLF YNFIKDRQTN KNDIKLFYKR LKKHLNLERI HTHRFRKTFA
     SILIENGLNI DDLQKIFDHS RIETTIKYVQ HNEKRALQEY KKYNDWGLN