VIP2_ARATH
ID VIP2_ARATH Reviewed; 614 AA.
AC Q9FPW4; Q8GZ37;
DT 08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT 08-MAR-2011, sequence version 2.
DT 25-MAY-2022, entry version 102.
DE RecName: Full=Probable NOT transcription complex subunit VIP2;
DE AltName: Full=Protein VIRE2 INTERACTING PROTEIN2;
DE Short=AtVIP2;
GN Name=VIP2; OrderedLocusNames=At5g59710; ORFNames=MTH12.8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9405937; DOI=10.1093/dnares/4.4.291;
RA Kotani H., Nakamura Y., Sato S., Kaneko T., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. II. Sequence
RT features of the regions of 1,044,062 bp covered by thirteen physically
RT assigned P1 clones.";
RL DNA Res. 4:291-300(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 24-614, FUNCTION, DISRUPTION PHENOTYPE,
RP INTERACTION WITH AGROBACTERIUM VIRE2 AND VIP1, AND SUBCELLULAR LOCATION.
RC STRAIN=cv. Columbia;
RX PubMed=17496122; DOI=10.1105/tpc.106.042903;
RA Anand A., Krichevsky A., Schornack S., Lahaye T., Tzfira T., Tang Y.,
RA Citovsky V., Mysore K.S.;
RT "Arabidopsis VIRE2 INTERACTING PROTEIN2 is required for Agrobacterium T-DNA
RT integration in plants.";
RL Plant Cell 19:1695-1708(2007).
CC -!- FUNCTION: Transcriptional regulator required for Agrobacterium-mediated
CC stable genetic transformation by T-DNA integration in host genome, but
CC not for T-DNA transient expression. {ECO:0000269|PubMed:17496122}.
CC -!- SUBUNIT: Interacts with Agrobacterium tumefaciens VirE2. Binds to VIP1.
CC Forms a complex made of Agrobacterium VirE2, VIP1, VIP2 and single-
CC stranded DNA (ssDNA). {ECO:0000269|PubMed:17496122}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:17496122}.
CC -!- DISRUPTION PHENOTYPE: Impaired stable genetic transformation by
CC Agrobacterium T-DNA. {ECO:0000269|PubMed:17496122}.
CC -!- SIMILARITY: Belongs to the CNOT2/3/5 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG44978.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=BAC41906.1; Type=Miscellaneous discrepancy; Note=Intron retention.; Evidence={ECO:0000305};
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DR EMBL; AB006705; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002688; AED97222.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM68181.1; -; Genomic_DNA.
DR EMBL; AK117230; BAC41906.1; ALT_SEQ; mRNA.
DR EMBL; AF295433; AAG44978.1; ALT_INIT; mRNA.
DR RefSeq; NP_001329954.1; NM_001345367.1.
DR RefSeq; NP_568912.2; NM_125363.3.
DR AlphaFoldDB; Q9FPW4; -.
DR SMR; Q9FPW4; -.
DR BioGRID; 21336; 4.
DR STRING; 3702.AT5G59710.1; -.
DR iPTMnet; Q9FPW4; -.
DR PaxDb; Q9FPW4; -.
DR PRIDE; Q9FPW4; -.
DR ProteomicsDB; 234239; -.
DR EnsemblPlants; AT5G59710.1; AT5G59710.1; AT5G59710.
DR EnsemblPlants; AT5G59710.2; AT5G59710.2; AT5G59710.
DR GeneID; 836092; -.
DR Gramene; AT5G59710.1; AT5G59710.1; AT5G59710.
DR Gramene; AT5G59710.2; AT5G59710.2; AT5G59710.
DR KEGG; ath:AT5G59710; -.
DR Araport; AT5G59710; -.
DR TAIR; locus:2174259; AT5G59710.
DR eggNOG; KOG2151; Eukaryota.
DR HOGENOM; CLU_016147_2_0_1; -.
DR InParanoid; Q9FPW4; -.
DR OMA; GMNRNQV; -.
DR OrthoDB; 1273874at2759; -.
DR PhylomeDB; Q9FPW4; -.
DR PRO; PR:Q9FPW4; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FPW4; baseline and differential.
DR Genevisible; Q9FPW4; AT.
DR GO; GO:0030015; C:CCR4-NOT core complex; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0000932; C:P-body; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; HDA:TAIR.
DR GO; GO:0015074; P:DNA integration; IMP:TAIR.
DR GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEP:UniProtKB.
DR Gene3D; 2.30.30.1020; -; 1.
DR InterPro; IPR038635; CCR4-NOT_su2/3/5_N_sf.
DR InterPro; IPR040168; Not2/3/5.
DR InterPro; IPR007282; NOT2/3/5_C.
DR PANTHER; PTHR23326; PTHR23326; 1.
DR Pfam; PF04153; NOT2_3_5; 1.
PE 1: Evidence at protein level;
KW Crown gall tumor; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..614
FT /note="Probable NOT transcription complex subunit VIP2"
FT /id="PRO_0000405594"
FT REGION 1..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 58..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 361..391
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 50
FT /note="I -> V (in Ref. 3; BAC41906)"
FT /evidence="ECO:0000305"
FT CONFLICT 193
FT /note="I -> V (in Ref. 3; BAC41906)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 614 AA; 66233 MW; 43D44D5CC49ED33A CRC64;
MSNLHSSLNG SASNLPDGSG RSFTASYSGQ SGAPSPSFHH TGNLQGLHNI HGNYNVGNMQ
GTLTSRNSSM NSIPSAGVQQ PNGSFSSGRF ASNNLPVNLS QLSHGSSHGH SGIPNRGLNV
VGNPGFSSNA NGVGGSIPGI LSTSAGLSNR NSVPGMGISQ LLGNSGPRIT NSMGNMVGGG
NLGRNISSGG LSIPGLSSRL NLAANSGSGL NVQGQNRMMG GVLPQGSQVM SMLGNSYHTG
GGPLSQNHVQ SVNNMMLSDH PNDSSLFDIN NDFPQLTSRP GSAGGTQGHL GSLRKQGLGV
PLVQQNQEFS IQNEDFPALP GYKGGNSEYP MDLHQKEQLH DNAMSMMHSQ NFSMGRSGGF
NLGATYSSHR PQQQPQHTSS TGGLQGLGLR PLSSPNAVSS IGYDQLIQQY QQHQNQSQFP
VQQMSSINQF RDSEMKSTQS EADPFCLLGL LDVLNRSNPE LTSLALGIDL TTLGLDLNST
GNLYKTFASP WTNEPAKSEV EFTVPNCYYA TEPPPLTRAS FKRFSYELLF YTFYSMPKDE
AQLYAADELY ERGWFYHKEL RVWFFRVGEP LVRAATYERG TYEYLDPNSF KTVRKEHFVI
KYELMEKRPS LLQL
