ID   VIP_GADMO               Reviewed;          25 AA.
AC   P09684;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1989, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Vasoactive intestinal peptide;
DE            Short=VIP;
DE   AltName: Full=Vasoactive intestinal polypeptide;
DE   Flags: Fragment;
GN   Name=vip;
OS   Gadus morhua (Atlantic cod).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Zeiogadaria; Gadariae; Gadiformes; Gadoidei; Gadidae; Gadus.
OX   NCBI_TaxID=8049;
RN   [1]
RP   PROTEIN SEQUENCE.
RA   Thwaites D.T., Young J., Thorndyke M.C., Dimaline R.;
RT   "Isolation and characterisation of two teleost VIP's.";
RL   Regul. Pept. 21:436-436(1988).
CC   -!- FUNCTION: VIP causes vasodilation, lowers arterial blood pressure,
CC       stimulates myocardial contractility, increases glycogenolysis and
CC       relaxes the smooth muscle of trachea, stomach and gall bladder.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the glucagon family. {ECO:0000305}.
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DR   PIR; JQ0361; JQ0361.
DR   AlphaFoldDB; P09684; -.
DR   SMR; P09684; -.
DR   Proteomes; UP000694546; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   GO; GO:0048255; P:mRNA stabilization; ISS:AgBase.
DR   GO; GO:0070459; P:prolactin secretion; ISS:AgBase.
DR   InterPro; IPR000532; Glucagon_GIP_secretin_VIP.
DR   Pfam; PF00123; Hormone_2; 1.
DR   PRINTS; PR00275; GLUCAGON.
DR   SMART; SM00070; GLUCA; 1.
DR   PROSITE; PS00260; GLUCAGON; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Hormone; Reference proteome; Secreted.
FT   PEPTIDE         1..>25
FT                   /note="Vasoactive intestinal peptide"
FT                   /id="PRO_0000045086"
FT   NON_TER         25
SQ   SEQUENCE   25 AA;  2978 MW;  1573FF6F374DB7E4 CRC64;
     HSDAVFTDNY SRFRKQMAAK KYLNS