ID   VIRB1_BRUAB             Reviewed;         238 AA.
AC   P0C398; Q57A14; Q9KIT0;
DT   29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=Type IV secretion system protein virB1;
GN   Name=virB1; OrderedLocusNames=BruAb2_0069;
OS   Brucella abortus biovar 1 (strain 9-941).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=262698;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=9-941;
RX   PubMed=15805518; DOI=10.1128/jb.187.8.2715-2726.2005;
RA   Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z.,
RA   Li L.-L., Kapur V., Alt D.P., Olsen S.C.;
RT   "Completion of the genome sequence of Brucella abortus and comparison to
RT   the highly similar genomes of Brucella melitensis and Brucella suis.";
RL   J. Bacteriol. 187:2715-2726(2005).
CC   -!- FUNCTION: The virB operon is essential for intracellular survival and
CC       is not involved in the invasion process. Constitutes a major
CC       determinant of virulence in mice (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the virb1 family. {ECO:0000305}.
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DR   EMBL; AE017224; AAX75520.1; -; Genomic_DNA.
DR   RefSeq; WP_002970474.1; NC_006933.1.
DR   AlphaFoldDB; P0C398; -.
DR   CAZy; GH23; Glycoside Hydrolase Family 23.
DR   EnsemblBacteria; AAX75520; AAX75520; BruAb2_0069.
DR   GeneID; 3827982; -.
DR   KEGG; bmb:BruAb2_0069; -.
DR   HOGENOM; CLU_076837_0_0_5; -.
DR   OMA; TNFRHYG; -.
DR   PRO; PR:P0C398; -.
DR   Proteomes; UP000000540; Chromosome II.
DR   InterPro; IPR023346; Lysozyme-like_dom_sf.
DR   InterPro; IPR008258; Transglycosylase_SLT_dom_1.
DR   Pfam; PF01464; SLT; 1.
DR   SUPFAM; SSF53955; SSF53955; 1.
PE   3: Inferred from homology;
KW   Virulence.
FT   CHAIN           1..238
FT                   /note="Type IV secretion system protein virB1"
FT                   /id="PRO_0000289552"
FT   REGION          197..238
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        197..217
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   238 AA;  25258 MW;  0C5AB5C13A45FE9E CRC64;
     MVPFLVLAQQ CAPTVAPQTM AAIVQVESGF NPYAIGVVGG RLVRQPVSLD EAITTAQSLE
     AKGWNFSLGI AQVNRYNLPK YGSTYAQAFD PCKNLKMGSK ILEDCYRRAI VKMPGQEQGA
     LRAAFSCYYA GNFTGGFKTK PGSPSYVQKV VASADVTTKP IVVVPMIRKT PDAAAAVAAP
     VKKRQPADRN SVLVDLHPSS QSMPATGTAN APVRLKTEQP ATTDAPPGKD NTDGVVVF