VIRB2_AGRFC
ID VIRB2_AGRFC Reviewed; 121 AA.
AC P17792;
DT 01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1990, sequence version 1.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=Protein virB2;
DE Flags: Precursor;
GN Name=virB2; OrderedLocusNames=Atu6168; ORFNames=AGR_pTi_4;
OS Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens
OS (strain C58)).
OG Plasmid pTiC58.
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium;
OC Agrobacterium tumefaciens complex.
OX NCBI_TaxID=176299;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2370849; DOI=10.1007/bf00261729;
RA Kuldau G.A., de Vos G., Owen J., McCaffrey G., Zambryski P.;
RT "The virB operon of Agrobacterium tumefaciens pTiC58 encodes 11 open
RT reading frames.";
RL Mol. Gen. Genet. 221:256-266(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2194232; DOI=10.1016/0147-619x(90)90028-b;
RA Rogowsky P.M., Powell B.S., Shirasu K., Lin T.-S., Morel P., Zyprian E.M.,
RA Steck T.R., Kado C.I.;
RT "Molecular characterization of the vir regulon of Agrobacterium
RT tumefaciens: complete nucleotide sequence and gene organization of the
RT 28.63-kbp regulon cloned as a single unit.";
RL Plasmid 23:85-106(1990).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2233252; DOI=10.1111/j.1365-2958.1990.tb00690.x;
RA Shirasu K., Morel P., Kado C.I.;
RT "Characterization of the virB operon of an Agrobacterium tumefaciens Ti
RT plasmid: nucleotide sequence and protein analysis.";
RL Mol. Microbiol. 4:1153-1163(1990).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=11743193; DOI=10.1126/science.1066804;
RA Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K.,
RA Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y.,
RA Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P.,
RA Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R.,
RA Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G.,
RA Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y.,
RA Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S.,
RA Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F.,
RA Gordon M.P., Olson M.V., Nester E.W.;
RT "The genome of the natural genetic engineer Agrobacterium tumefaciens
RT C58.";
RL Science 294:2317-2323(2001).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C58 / ATCC 33970;
RX PubMed=11743194; DOI=10.1126/science.1066803;
RA Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B.,
RA Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K.,
RA Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M.,
RA Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C.,
RA Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
RT "Genome sequence of the plant pathogen and biotechnology agent
RT Agrobacterium tumefaciens C58.";
RL Science 294:2323-2328(2001).
CC -!- FUNCTION: VirB proteins are suggested to act at the bacterial surface
CC and there play an important role in directing T-DNA transfer to plant
CC cells.
CC -!- SUBUNIT: Interacts with host plant RTNLB1 protein. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the virB2 family. {ECO:0000305}.
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DR EMBL; X53264; CAA37355.1; -; Genomic_DNA.
DR EMBL; J03320; AAA91592.1; -; Genomic_DNA.
DR EMBL; AE007871; AAK90929.1; -; Genomic_DNA.
DR PIR; AF3248; AF3248.
DR PIR; S12342; B2AG58.
DR RefSeq; NP_396488.1; NC_003065.3.
DR RefSeq; WP_010891502.1; NC_003065.3.
DR AlphaFoldDB; P17792; -.
DR IntAct; P17792; 1.
DR EnsemblBacteria; AAK90929; AAK90929; Atu6168.
DR GeneID; 39477133; -.
DR KEGG; atu:Atu6168; -.
DR PATRIC; fig|176299.10.peg.5364; -.
DR HOGENOM; CLU_165260_0_0_5; -.
DR OMA; TMVNNIC; -.
DR BioCyc; AGRO:ATU6168-MON; -.
DR Proteomes; UP000000813; Plasmid Ti.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0043684; C:type IV secretion system complex; IGC:PAMGO_GAT.
DR GO; GO:0030255; P:protein secretion by the type IV secretion system; IGC:PAMGO_GAT.
DR InterPro; IPR007039; TrbC/VirB2.
DR Pfam; PF04956; TrbC; 1.
PE 3: Inferred from homology;
KW Cell outer membrane; Crown gall tumor; Membrane; Plasmid;
KW Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT SIGNAL 1..19
FT /evidence="ECO:0000255"
FT CHAIN 20..121
FT /note="Protein virB2"
FT /id="PRO_0000022660"
FT TRANSMEM 65..85
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 94..114
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 121 AA; 12318 MW; 0499B92984A417AE CRC64;
MRCFERYRVH LNRLSLSNAV MRMVSGYAPS VVGAMGWSIF SSGPAAAQSA GGGTDPATMV
NNICTFILGP FGQSLAVLGI VAIGISWMFG RASLGLVAGV VGGIVIMFGA SFLGKTLTGG
G
