ID   VIRB2_BRUME             Reviewed;         105 AA.
AC   Q9RPY3;
DT   12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Type IV secretion system protein virB2;
DE   Flags: Precursor;
GN   Name=virB2; OrderedLocusNames=BMEII0026;
OS   Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=224914;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=63/290;
RA   Wang Y., Chen C., Cao X.;
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=16M / ATCC 23456 / NCTC 10094;
RX   PubMed=11756688; DOI=10.1073/pnas.221575398;
RA   DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T.,
RA   Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G.,
RA   Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E.,
RA   Selkov E., Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J.,
RA   Haselkorn R., Kyrpides N.C., Overbeek R.;
RT   "The genome sequence of the facultative intracellular pathogen Brucella
RT   melitensis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the PtlA family. {ECO:0000305}.
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DR   EMBL; EF208926; ABM66830.1; -; Genomic_DNA.
DR   EMBL; AE008918; AAL53267.1; -; Genomic_DNA.
DR   PIR; AH3512; AH3512.
DR   RefSeq; WP_002967165.1; NZ_GG703779.1.
DR   AlphaFoldDB; Q9RPY3; -.
DR   STRING; 224914.BMEII0026; -.
DR   EnsemblBacteria; AAL53267; AAL53267; BMEII0026.
DR   GeneID; 45125487; -.
DR   GeneID; 55591805; -.
DR   KEGG; bme:BMEII0026; -.
DR   PATRIC; fig|224914.52.peg.2194; -.
DR   eggNOG; ENOG5033CNI; Bacteria.
DR   OMA; TIMIAWA; -.
DR   Proteomes; UP000000419; Chromosome II.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007039; TrbC/VirB2.
DR   Pfam; PF04956; TrbC; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Signal; Transmembrane; Transmembrane helix;
KW   Virulence.
FT   SIGNAL          1..36
FT                   /evidence="ECO:0000255"
FT   CHAIN           37..105
FT                   /note="Type IV secretion system protein virB2"
FT                   /id="PRO_0000291451"
FT   TRANSMEM        50..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        83..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   105 AA;  11107 MW;  837E9B32EA02B120 CRC64;
     MKTASPSKKS LSRILPHLLL ALIVSIAAIE PNLAHANGGL DKVNTSMQKV LDLLSGVSIT
     IVTIAIIWSG YKMAFRHARF MDVVPVLGGA LVVGAAAEIA SYLLR