ID   VIRB4_AGRT9             Reviewed;         789 AA.
AC   P0A3W1; P05353; P05354; P09777;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 48.
DE   RecName: Full=Protein virB4;
DE   Flags: Precursor;
GN   Name=virB4;
OS   Agrobacterium tumefaciens (strain 15955).
OG   Plasmid pTi15955.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium;
OC   Agrobacterium tumefaciens complex.
OX   NCBI_TaxID=190386;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2837739; DOI=10.1093/nar/16.10.4621;
RA   Thompson D.V., Melchers L.S., Idler K.B., Shilperoort R.A.,
RA   Hooykaas P.J.J.;
RT   "Analysis of the complete nucleotide sequence of the Agrobacterium
RT   tumefaciens virB operon.";
RL   Nucleic Acids Res. 16:4621-4636(1988).
CC   -!- FUNCTION: A possible function of virB4 might be to provide the energy,
CC       via hydrolysis of ATP, for translocation of virulence proteins of the
CC       transfer of a T-DNA-protein complex across the agrobacterium membrane.
CC   -!- SIMILARITY: Belongs to the TrbE/VirB4 family. {ECO:0000305}.
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DR   EMBL; X06826; CAA29975.1; -; Genomic_DNA.
DR   PIR; A30402; B4AGA6.
DR   RefSeq; NP_059802.1; NC_002377.1.
DR   AlphaFoldDB; P0A3W1; -.
DR   SMR; P0A3W1; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR004346; CagE_TrbE_VirB.
DR   InterPro; IPR018145; CagE_TrbE_VirB_cntrl_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF03135; CagE_TrbE_VirB; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00929; VirB4_CagE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Crown gall tumor; Nucleotide-binding; Plasmid; Signal.
FT   SIGNAL          1..38
FT                   /evidence="ECO:0000255"
FT   CHAIN           39..789
FT                   /note="Protein virB4"
FT                   /id="PRO_0000022664"
FT   BINDING         433..440
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   789 AA;  87361 MW;  93A8A5E80AA10298 CRC64;
     MLGASGTTER SGEIYLPYIG HLSDHIVLLE DGSIMSIARI DGVAFELEEI EMRNARCRAF
     NTLLRNIADD HVSIYAHLVR HADVPSSAPR HFRSVFAASL NEAFEQRVLS GQLLRNDHFL
     TLIVYPQAAL GKVKRRFTKL SGKRENDLAG QIRNMEDLWH VVAGSLKAYG LHRLGIREKQ
     GVLFTEIGEA LRLIMTGRFT PVPVVSGSLG ASIYTDRVIC GKRGLEIRTP KDSYVGSIYS
     FREYPAKTRP GMLNALLSLD FPLVLTQSFS FLTRPQAHAK LSLKSSQMLS SGDKAVTQIG
     KLSEAEDALA SNEFVMGSHH LSLCVYADDL NSLGDRGARA RTRMADAGAV VVQEGIGMEA
     AYWSQLPGNF KWRTRPGAIT SRNFAGFVSF ENFPEGASSG HWGTAIARFR TNGGTPFDYI
     PHEHDVGMTA IFGPIGRGKT TLMMFVLAML EQSMVDRAGT VVFFDKDRGG ELLVRATGGT
     YLALRRGTPS GLAPLRGLEN TAASHDFLRE WIVALIESDG RGGISPEENR RLVRGIHRQL
     SFDPQMRSIA GLREFLLHGP AEGAGARLQR WCRGHALGWA FDGEVDEVKL DPSITGFDMT
     HLLEYEEVCA PAAAYLLHRI GAMIDGRRFV MSCDEFRAYL LNPKFSAVVD KFLLTVRKNN
     GMLILATQQP EHVLESPLGA SLVAQCMTKI FYPSPTADRS AYIDGLKCTE KEFQAIREDM
     TVGSRKFLLK RESGSVICEF DLRDMREYVA VLSGRANTVR FAARLREAQE GNSSGWLSEF
     MARHHEAED