VIRB6_AGRFC
ID VIRB6_AGRFC Reviewed; 295 AA.
AC P17796;
DT 01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1990, sequence version 2.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=Protein VirB6;
GN Name=virB6; OrderedLocusNames=Atu6172; ORFNames=AGR_pTi_10;
OS Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens
OS (strain C58)).
OG Plasmid pTiC58.
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium;
OC Agrobacterium tumefaciens complex.
OX NCBI_TaxID=176299;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2370849; DOI=10.1007/bf00261729;
RA Kuldau G.A., de Vos G., Owen J., McCaffrey G., Zambryski P.;
RT "The virB operon of Agrobacterium tumefaciens pTiC58 encodes 11 open
RT reading frames.";
RL Mol. Gen. Genet. 221:256-266(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2194232; DOI=10.1016/0147-619x(90)90028-b;
RA Rogowsky P.M., Powell B.S., Shirasu K., Lin T.-S., Morel P., Zyprian E.M.,
RA Steck T.R., Kado C.I.;
RT "Molecular characterization of the vir regulon of Agrobacterium
RT tumefaciens: complete nucleotide sequence and gene organization of the
RT 28.63-kbp regulon cloned as a single unit.";
RL Plasmid 23:85-106(1990).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2233252; DOI=10.1111/j.1365-2958.1990.tb00690.x;
RA Shirasu K., Morel P., Kado C.I.;
RT "Characterization of the virB operon of an Agrobacterium tumefaciens Ti
RT plasmid: nucleotide sequence and protein analysis.";
RL Mol. Microbiol. 4:1153-1163(1990).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=11743193; DOI=10.1126/science.1066804;
RA Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K.,
RA Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y.,
RA Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P.,
RA Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R.,
RA Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G.,
RA Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y.,
RA Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S.,
RA Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F.,
RA Gordon M.P., Olson M.V., Nester E.W.;
RT "The genome of the natural genetic engineer Agrobacterium tumefaciens
RT C58.";
RL Science 294:2317-2323(2001).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C58 / ATCC 33970;
RX PubMed=11743194; DOI=10.1126/science.1066803;
RA Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B.,
RA Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K.,
RA Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M.,
RA Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C.,
RA Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
RT "Genome sequence of the plant pathogen and biotechnology agent
RT Agrobacterium tumefaciens C58.";
RL Science 294:2323-2328(2001).
CC -!- FUNCTION: VirB proteins are suggested to act at the bacterial surface
CC and there play an important role in directing T-DNA transfer to plant
CC cells.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the TrbL/VirB6 family. {ECO:0000305}.
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DR EMBL; X53264; CAA37359.1; -; Genomic_DNA.
DR EMBL; J03320; AAA91596.1; -; Genomic_DNA.
DR EMBL; AE007871; AAK90934.2; -; Genomic_DNA.
DR PIR; AB3249; AB3249.
DR PIR; S12346; B6AG58.
DR RefSeq; NP_396493.2; NC_003065.3.
DR RefSeq; WP_010974917.1; NC_003065.3.
DR AlphaFoldDB; P17796; -.
DR EnsemblBacteria; AAK90934; AAK90934; Atu6172.
DR GeneID; 39477129; -.
DR KEGG; atu:Atu6172; -.
DR PATRIC; fig|176299.10.peg.5368; -.
DR HOGENOM; CLU_914913_0_0_5; -.
DR OMA; LWIIVQG; -.
DR PhylomeDB; P17796; -.
DR BioCyc; AGRO:ATU6172-MON; -.
DR Proteomes; UP000000813; Plasmid Ti.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0043684; C:type IV secretion system complex; IGC:PAMGO_GAT.
DR GO; GO:0030255; P:protein secretion by the type IV secretion system; IGC:PAMGO_GAT.
DR InterPro; IPR007688; Conjugal_tfr_TrbL/VirB6.
DR Pfam; PF04610; TrbL; 1.
PE 3: Inferred from homology;
KW Crown gall tumor; Membrane; Plasmid; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..295
FT /note="Protein VirB6"
FT /id="PRO_0000065840"
FT TRANSMEM 35..55
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 68..88
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 167..187
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 201..221
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 226..246
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 251..271
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 268
FT /note="Missing (in Ref. 2 and 3)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 295 AA; 31860 MW; 055C9A0776562335 CRC64;
MNFTIPAPFT AIHTIFDLAF TTSLDTMLGT IQEAVSAPLV ACVTLWIIVQ GILVMRGEID
TRGGITRVIT VTVVVALVVG QANYHDYVVS VFEETIPNFI QQFSGSGLPL QTIPAQLDTM
FALTQAAFQR IASEIGPMND QDILAFQGAQ WVFYGTLWSA FGIYDAVGIL TKVLLAIGPL
ILTGYIFDRT RDIAAKWIGQ LITYGLLLLL LNLVATIVIL TEATALTLML GVITLAGTTA
AKIIGLYELD MFFLTGDALI VALPAIAGNI GGSYWSGATQ SANSLYRRFA QVDRR
