ID   VIRB6_BRUME             Reviewed;         347 AA.
AC   Q8YDZ2;
DT   12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Type IV secretion system protein VirB6;
GN   Name=virB6; OrderedLocusNames=BMEII0030;
OS   Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=224914;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=16M / ATCC 23456 / NCTC 10094;
RX   PubMed=11756688; DOI=10.1073/pnas.221575398;
RA   DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T.,
RA   Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G.,
RA   Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E.,
RA   Selkov E., Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J.,
RA   Haselkorn R., Kyrpides N.C., Overbeek R.;
RT   "The genome sequence of the facultative intracellular pathogen Brucella
RT   melitensis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TrbL/VirB6 family. {ECO:0000305}.
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DR   EMBL; AE008918; AAL53271.1; -; Genomic_DNA.
DR   PIR; AD3513; AD3513.
DR   RefSeq; WP_004686828.1; NZ_GG703779.1.
DR   AlphaFoldDB; Q8YDZ2; -.
DR   STRING; 224914.BMEII0030; -.
DR   EnsemblBacteria; AAL53271; AAL53271; BMEII0030.
DR   GeneID; 29596002; -.
DR   KEGG; bme:BMEII0030; -.
DR   PATRIC; fig|224914.52.peg.2190; -.
DR   eggNOG; COG3704; Bacteria.
DR   OMA; FIVQMFA; -.
DR   PhylomeDB; Q8YDZ2; -.
DR   Proteomes; UP000000419; Chromosome II.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030255; P:protein secretion by the type IV secretion system; IEA:InterPro.
DR   InterPro; IPR007688; Conjugal_tfr_TrbL/VirB6.
DR   Pfam; PF04610; TrbL; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Virulence.
FT   CHAIN           1..347
FT                   /note="Type IV secretion system protein VirB6"
FT                   /id="PRO_0000290182"
FT   TRANSMEM        32..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        153..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        177..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        205..225
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        245..265
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        270..290
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   347 AA;  36175 MW;  32ABBB639420053F CRC64;
     MVNPVIFEFI GTSIHNQLNN YVTMVASNTM NMIATTAVLA GGLYYTAMGI LMSVGRIEGP
     FSQLVISCIK FMLIAAFALN ISTYSEWVID TVHNMESGFA DAFAGNHGTP SSTIYQTLDN
     SLGKGWNIAA MLFEKGDNRG LTQIVQGFSE LLLSFLVAGS TLILAGPTGA MIVATNAVIA
     ILLGIGPLFI LALGWAPTRG FFDRWFGTIV TSILQVALLS AVLSISSAIF SRMVAAINLA
     SATQSTLFSC LSLTAVTIVM PYMMYKVYEY GGILGSSISA ATISLGSLAV NTAKSGGGAM
     TSIFSGSSGG GGSGSAKAGG ESSYSAGGNA MWSPAFRQHV LGQFNRD