ID   VIRB8_BRUAB             Reviewed;         239 AA.
AC   P0C532; Q57A21; Q7BMZ6;
DT   12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Type IV secretion system protein virB8;
GN   Name=virB8; OrderedLocusNames=BruAb2_0062;
OS   Brucella abortus biovar 1 (strain 9-941).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=262698;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=9-941;
RX   PubMed=15805518; DOI=10.1128/jb.187.8.2715-2726.2005;
RA   Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z.,
RA   Li L.-L., Kapur V., Alt D.P., Olsen S.C.;
RT   "Completion of the genome sequence of Brucella abortus and comparison to
RT   the highly similar genomes of Brucella melitensis and Brucella suis.";
RL   J. Bacteriol. 187:2715-2726(2005).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Single-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the virB8 family. {ECO:0000305}.
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DR   EMBL; AE017224; AAX75513.1; -; Genomic_DNA.
DR   RefSeq; WP_002966517.1; NC_006933.1.
DR   AlphaFoldDB; P0C532; -.
DR   SMR; P0C532; -.
DR   EnsemblBacteria; AAX75513; AAX75513; BruAb2_0062.
DR   GeneID; 45053159; -.
DR   GeneID; 55591799; -.
DR   KEGG; bmb:BruAb2_0062; -.
DR   HOGENOM; CLU_068461_1_1_5; -.
DR   OMA; DLIQVRY; -.
DR   PRO; PR:P0C532; -.
DR   Proteomes; UP000000540; Chromosome II.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030255; P:protein secretion by the type IV secretion system; IEA:InterPro.
DR   InterPro; IPR032710; NTF2-like_dom_sf.
DR   InterPro; IPR007430; VirB8.
DR   InterPro; IPR026264; VirB8/PtlE.
DR   Pfam; PF04335; VirB8; 1.
DR   PIRSF; PIRSF003299; VirB8_PtlE; 1.
DR   SUPFAM; SSF54427; SSF54427; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Virulence.
FT   CHAIN           1..239
FT                   /note="Type IV secretion system protein virB8"
FT                   /id="PRO_0000291390"
FT   TRANSMEM        47..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   239 AA;  26446 MW;  68F44CBCF7018023 CRC64;
     MFGRKQSPQK SVKNGQGNAP SVYDEALNWE AAHVRLVEKS ERRAWKIAGA FGTITVLLGI
     GIAGMLPLKQ HVPYLVRVNA QTGAPDILTS LDEKSVSYDT VMDKYWLSQY VIARETYDWY
     TLQKDYETVG MLSSPSEGQS YASQFQGDKA LDKQYGSNVR TSVTIVSIVP NGKGIGTVRF
     AKTTKRTNET GDGETTHWIA TIGYQYVNPS LMSESARLTN PLGFNVTSYR VDPEMGVVQ