ID   VIRBA_BRUO2             Reviewed;         380 AA.
AC   Q0GK35; A5VTI1;
DT   12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 2.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Type IV secretion system protein virB10;
GN   Name=virB10; OrderedLocusNames=BOV_A0055;
OS   Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=444178;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Wang Y., Chen C., Liu J.;
RT   "virB10 gene of Brucella ovis 63/290.";
RL   Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25840 / 63/290 / NCTC 10512;
RX   PubMed=19436743; DOI=10.1371/journal.pone.0005519;
RA   Tsolis R.M., Seshadri R., Santos R.L., Sangari F.J., Lobo J.M.,
RA   de Jong M.F., Ren Q., Myers G., Brinkac L.M., Nelson W.C., Deboy R.T.,
RA   Angiuoli S., Khouri H., Dimitrov G., Robinson J.R., Mulligan S.,
RA   Walker R.L., Elzer P.E., Hassan K.A., Paulsen I.T.;
RT   "Genome degradation in Brucella ovis corresponds with narrowing of its host
RT   range and tissue tropism.";
RL   PLoS ONE 4:E5519-E5519(2009).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TrbI/VirB10 family. {ECO:0000305}.
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DR   EMBL; DQ861303; ABI23036.1; -; Genomic_DNA.
DR   EMBL; CP000709; ABQ61987.1; -; Genomic_DNA.
DR   RefSeq; WP_006014994.1; NC_009504.1.
DR   AlphaFoldDB; Q0GK35; -.
DR   SMR; Q0GK35; -.
DR   EnsemblBacteria; ABQ61987; ABQ61987; BOV_A0055.
DR   GeneID; 45125479; -.
DR   KEGG; bov:BOV_A0055; -.
DR   HOGENOM; CLU_041899_2_1_5; -.
DR   OMA; PGKDRNT; -.
DR   PhylomeDB; Q0GK35; -.
DR   Proteomes; UP000006383; Chromosome II.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd16429; VirB10; 1.
DR   Gene3D; 2.40.128.260; -; 2.
DR   InterPro; IPR005498; T4SS_VirB10/TraB/TrbI.
DR   InterPro; IPR042217; T4SS_VirB10/TrbI.
DR   Pfam; PF03743; TrbI; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix; Virulence.
FT   CHAIN           1..380
FT                   /note="Type IV secretion system protein virB10"
FT                   /id="PRO_0000291387"
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          78..102
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        148
FT                   /note="T -> TAGDTVVQT (in Ref. 1; ABI23036)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        309
FT                   /note="F -> L (in Ref. 1; ABI23036)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        378
FT                   /note="K -> Q (in Ref. 1; ABI23036)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   380 AA;  40455 MW;  1360270C53DB1BCF CRC64;
     MTQENIPVQP GTLDGERGLP TVNENGSGRT RKVLLFLFVV GFIVVLLLLL VFHMRGNAEN
     NHHSDKTMVQ TSTVPMRTFK LPPPPPPAPP EPPAPPPAPA MPIAEPAAAA LSLPPLPDDT
     PAKDDVLDKS ASALMVVTKS SGDTNAQTTN ARIQALLDSQ KNTKQDAGSL GTLLHGTQTD
     ARMASLLRNR DFLLAKGSII NCALQTRLDS TVPGMAACVV TRNMYSDNGK VLLIERGSTI
     SGEYDANVKQ GMARIYVLWT RVKTPNGVVI DLDSPGADPL GGAGLPGYID SHFWKRFGGA
     LMLSTIETFG RYATQKVGGG GSNQINLNTG GGESTSNLAS TALKDTINIP PTLYKNQGEE
     IGIYIARDLD FSSVYDVKPK