ID   VIRC2_AGRFC             Reviewed;         202 AA.
AC   P07166;
DT   01-APR-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1988, sequence version 1.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=Protein virC2;
GN   Name=virC2; OrderedLocusNames=Atu6179; ORFNames=AGR_pTi_16;
OS   Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens
OS   (strain C58)).
OG   Plasmid pTiC58.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium;
OC   Agrobacterium tumefaciens complex.
OX   NCBI_TaxID=176299;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3584058; DOI=10.1128/jb.169.6.2336-2344.1987;
RA   Close T.J., Tait R.C., Rempel H.C., Hirooka T., Kim L., Kado C.I.;
RT   "Molecular characterization of the virC genes of the Ti plasmid.";
RL   J. Bacteriol. 169:2336-2344(1987).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2194232; DOI=10.1016/0147-619x(90)90028-b;
RA   Rogowsky P.M., Powell B.S., Shirasu K., Lin T.-S., Morel P., Zyprian E.M.,
RA   Steck T.R., Kado C.I.;
RT   "Molecular characterization of the vir regulon of Agrobacterium
RT   tumefaciens: complete nucleotide sequence and gene organization of the
RT   28.63-kbp regulon cloned as a single unit.";
RL   Plasmid 23:85-106(1990).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11743193; DOI=10.1126/science.1066804;
RA   Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K.,
RA   Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y.,
RA   Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P.,
RA   Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R.,
RA   Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G.,
RA   Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y.,
RA   Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S.,
RA   Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F.,
RA   Gordon M.P., Olson M.V., Nester E.W.;
RT   "The genome of the natural genetic engineer Agrobacterium tumefaciens
RT   C58.";
RL   Science 294:2317-2323(2001).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C58 / ATCC 33970;
RX   PubMed=11743194; DOI=10.1126/science.1066803;
RA   Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B.,
RA   Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K.,
RA   Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M.,
RA   Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C.,
RA   Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
RT   "Genome sequence of the plant pathogen and biotechnology agent
RT   Agrobacterium tumefaciens C58.";
RL   Science 294:2323-2328(2001).
CC   -!- INTERACTION:
CC       P07166; P07165: virC1; NbExp=3; IntAct=EBI-7412655, EBI-7412683;
CC   -!- MISCELLANEOUS: The Ti plasmid contains at least six transcriptional
CC       units, designated vir loci, which are essential for efficient crown-
CC       gall tumorigenesis.
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DR   EMBL; Y00535; CAA68596.1; -; Genomic_DNA.
DR   EMBL; M16397; AAA98387.1; -; Genomic_DNA.
DR   EMBL; J03320; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AE007871; AAK90941.2; -; Genomic_DNA.
DR   PIR; AI3249; AI3249.
DR   PIR; B25975; B25975.
DR   RefSeq; NP_396500.2; NC_003065.3.
DR   RefSeq; WP_010891491.1; NC_003065.3.
DR   PDB; 2RH3; X-ray; 1.70 A; A=82-202.
DR   PDBsum; 2RH3; -.
DR   AlphaFoldDB; P07166; -.
DR   SMR; P07166; -.
DR   IntAct; P07166; 2.
DR   MINT; P07166; -.
DR   EnsemblBacteria; AAK90941; AAK90941; Atu6179.
DR   GeneID; 39477122; -.
DR   KEGG; atu:Atu6179; -.
DR   PATRIC; fig|176299.10.peg.5373; -.
DR   HOGENOM; CLU_1352254_0_0_5; -.
DR   OMA; QTSRMFP; -.
DR   BioCyc; AGRO:ATU6179-MON; -.
DR   EvolutionaryTrace; P07166; -.
DR   Proteomes; UP000000813; Plasmid Ti.
DR   GO; GO:0003677; F:DNA binding; IGC:PAMGO_GAT.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.10.1220.190; -; 1.
DR   InterPro; IPR010985; Ribbon_hlx_hlx.
DR   InterPro; IPR009841; VirC2.
DR   InterPro; IPR038473; VirC2_C_sf.
DR   Pfam; PF07181; VirC2; 1.
DR   PIRSF; PIRSF016094; VirC2; 1.
DR   SUPFAM; SSF47598; SSF47598; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Crown gall tumor; Plasmid; Reference proteome.
FT   CHAIN           1..202
FT                   /note="Protein virC2"
FT                   /id="PRO_0000065853"
FT   REGION          21..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        42..56
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   STRAND          83..88
FT                   /evidence="ECO:0007829|PDB:2RH3"
FT   HELIX           97..102
FT                   /evidence="ECO:0007829|PDB:2RH3"
FT   TURN            103..105
FT                   /evidence="ECO:0007829|PDB:2RH3"
FT   HELIX           108..128
FT                   /evidence="ECO:0007829|PDB:2RH3"
FT   HELIX           131..134
FT                   /evidence="ECO:0007829|PDB:2RH3"
FT   STRAND          152..157
FT                   /evidence="ECO:0007829|PDB:2RH3"
FT   HELIX           160..170
FT                   /evidence="ECO:0007829|PDB:2RH3"
FT   HELIX           178..199
FT                   /evidence="ECO:0007829|PDB:2RH3"
SQ   SEQUENCE   202 AA;  22075 MW;  4DD8C5F96C81F28F CRC64;
     MGIRKPALSV GEARRLAAAR PEIVHPSLPV ATQNSTLPQP PENLDEEDRR PAPATAKRCH
     SSDQQSMLTV DALSSTTAPE KIQVFLSARP PAPEVSKIYD NLILQYSPSK SLQMILRRAL
     GDFENMLADG SFRAAPKSYP IPHTAFEKSI IVQTSRMFPV SLIEAARNHF DPLGLETARA
     FGHKLATAAL ACFFAREKAT NS