ID   VIRE1_AGRFC             Reviewed;          63 AA.
AC   P08063;
DT   01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1988, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Protein virE1;
DE   AltName: Full=7.1 kDa virulence protein;
GN   Name=virE1; OrderedLocusNames=Atu6189; ORFNames=AGR_pTi_26;
OS   Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens
OS   (strain C58)).
OG   Plasmid pTiC58.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium;
OC   Agrobacterium tumefaciens complex.
OX   NCBI_TaxID=176299;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3549694; DOI=10.1128/jb.169.4.1529-1536.1987;
RA   Hirooka T., Rogowsky P.M., Kado C.I.;
RT   "Characterization of the virE locus of Agrobacterium tumefaciens plasmid
RT   pTiC58.";
RL   J. Bacteriol. 169:1529-1536(1987).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2194232; DOI=10.1016/0147-619x(90)90028-b;
RA   Rogowsky P.M., Powell B.S., Shirasu K., Lin T.-S., Morel P., Zyprian E.M.,
RA   Steck T.R., Kado C.I.;
RT   "Molecular characterization of the vir regulon of Agrobacterium
RT   tumefaciens: complete nucleotide sequence and gene organization of the
RT   28.63-kbp regulon cloned as a single unit.";
RL   Plasmid 23:85-106(1990).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11743193; DOI=10.1126/science.1066804;
RA   Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K.,
RA   Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y.,
RA   Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P.,
RA   Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R.,
RA   Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G.,
RA   Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y.,
RA   Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S.,
RA   Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F.,
RA   Gordon M.P., Olson M.V., Nester E.W.;
RT   "The genome of the natural genetic engineer Agrobacterium tumefaciens
RT   C58.";
RL   Science 294:2317-2323(2001).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C58 / ATCC 33970;
RX   PubMed=11743194; DOI=10.1126/science.1066803;
RA   Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B.,
RA   Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K.,
RA   Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M.,
RA   Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C.,
RA   Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
RT   "Genome sequence of the plant pathogen and biotechnology agent
RT   Agrobacterium tumefaciens C58.";
RL   Science 294:2323-2328(2001).
RN   [5]
RP   X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) IN COMPLEX WITH VIRE2, AND FUNCTION.
RX   PubMed=18678909; DOI=10.1073/pnas.0801525105;
RA   Dym O., Albeck S., Unger T., Jacobovitch J., Branzburg A., Michael Y.,
RA   Frenkiel-Krispin D., Wolf S.G., Elbaum M.;
RT   "Crystal structure of the Agrobacterium virulence complex VirE1-VirE2
RT   reveals a flexible protein that can accommodate different partners.";
RL   Proc. Natl. Acad. Sci. U.S.A. 105:11170-11175(2008).
CC   -!- FUNCTION: Involved in DNA transformation; controls virE2 polymerization
CC       and prevents virE2 binding to DNA. {ECO:0000269|PubMed:18678909}.
CC   -!- SUBUNIT: Forms heterodimers with virE2 that prevent virE2 anarchic
CC       homopolymerization and binding to DNA. {ECO:0000269|PubMed:18678909}.
CC   -!- MISCELLANEOUS: The Ti plasmid contains at least six transcriptional
CC       units, designated vir loci, which are essential for efficient crown-
CC       gall tumorigenesis.
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DR   EMBL; M15814; AAA98371.1; -; Genomic_DNA.
DR   EMBL; J03320; AAA91609.1; -; Genomic_DNA.
DR   EMBL; AE007871; AAK90950.1; -; Genomic_DNA.
DR   PIR; AC3251; AC3251.
DR   PIR; S11844; S11844.
DR   RefSeq; NP_396509.1; NC_003065.3.
DR   RefSeq; WP_010891482.1; NC_003065.3.
DR   PDB; 3BTP; X-ray; 2.30 A; B=1-63.
DR   PDBsum; 3BTP; -.
DR   AlphaFoldDB; P08063; -.
DR   SMR; P08063; -.
DR   DIP; DIP-46169N; -.
DR   IntAct; P08063; 1.
DR   EnsemblBacteria; AAK90950; AAK90950; Atu6189.
DR   GeneID; 39477112; -.
DR   KEGG; atu:Atu6189; -.
DR   HOGENOM; CLU_2846756_0_0_5; -.
DR   OMA; PQEIHKE; -.
DR   BioCyc; AGRO:ATU6189-MON; -.
DR   EvolutionaryTrace; P08063; -.
DR   Proteomes; UP000000813; Plasmid Ti.
DR   GO; GO:0006457; P:protein folding; TAS:PAMGO_GAT.
DR   InterPro; IPR024237; VirE1.
DR   Pfam; PF12189; VirE1; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Crown gall tumor; Plasmid; Reference proteome; Virulence.
FT   CHAIN           1..63
FT                   /note="Protein virE1"
FT                   /id="PRO_0000065864"
FT   TURN            32..36
FT                   /evidence="ECO:0007829|PDB:3BTP"
FT   HELIX           39..52
FT                   /evidence="ECO:0007829|PDB:3BTP"
SQ   SEQUENCE   63 AA;  7149 MW;  A6553375185BB88C CRC64;
     MVIIKLNANK NMPVLAVEKP QEIHKEELSD HHQSNGFTSL DLEMIELENF VLHCPLPEEN
     LAG