ID   VIRE2_HELVI             Reviewed;          44 AA.
AC   P86354;
DT   23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   23-MAR-2010, sequence version 1.
DT   02-JUN-2021, entry version 21.
DE   RecName: Full=Viresin {ECO:0000303|PubMed:10651803};
DE   Flags: Fragment;
OS   Heliothis virescens (Tobacco budworm moth).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;
OC   Noctuidae; Heliothinae; Heliothis.
OX   NCBI_TaxID=7102;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, FUNCTION, AND SUBCELLULAR LOCATION.
RC   TISSUE=Hemolymph {ECO:0000269|PubMed:10651803};
RX   PubMed=10651803; DOI=10.1046/j.1432-1327.2000.01034.x;
RA   Chung K.T., Ourth D.D.;
RT   "Viresin. A novel antibacterial protein from immune hemolymph of Heliothis
RT   virescens pupae.";
RL   Eur. J. Biochem. 267:677-683(2000).
CC   -!- FUNCTION: Has antibacterial activity against the Gram-negative bacteria
CC       E.coli and E.cloacae, but not against the Gram-negative bacteria
CC       P.aeruginosa, P.vulgaris, K.pneumoniae and S.enteritidis or the Gram-
CC       positive bacteria S.aureus, S.epidermidis and S.salivarius.
CC       {ECO:0000269|PubMed:10651803}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:10651803}.
CC   -!- SIMILARITY: Belongs to the insect A10/OS-D protein family.
CC       {ECO:0000305}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.2080.10; -; 1.
DR   InterPro; IPR005055; A10/PebIII.
DR   InterPro; IPR036682; OS_D_A10/PebIII_sf.
DR   Pfam; PF03392; OS-D; 1.
DR   SUPFAM; SSF100910; SSF100910; 1.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Direct protein sequencing; Secreted.
FT   CHAIN           1..>44
FT                   /note="Viresin"
FT                   /id="PRO_0000392511"
FT   NON_TER         44
FT                   /evidence="ECO:0000303|PubMed:10651803"
SQ   SEQUENCE   44 AA;  5062 MW;  F923BDD6F0CCA0CA CRC64;
     YDNVNLDEIL ANDRLLVPYI KCLLDEGKKA PDAKELKEHI RXAL