ID   VIS_AGRVS               Reviewed;         360 AA.
AC   Q04554; B9K444;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=Vitopine synthase;
DE            EC=1.5.1.-;
GN   Name=vis; OrderedLocusNames=Avi_8271;
OS   Agrobacterium vitis (strain S4 / ATCC BAA-846) (Rhizobium vitis (strain
OS   S4)).
OG   Plasmid pTiS4.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium.
OX   NCBI_TaxID=311402;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1465104; DOI=10.1007/bf00279373;
RA   Canaday J., Gerard J.-C., Crouzet P., Otten L.;
RT   "Organization and functional analysis of three T-DNAs from the vitopine Ti
RT   plasmid pTiS4.";
RL   Mol. Gen. Genet. 235:292-303(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S4 / ATCC BAA-846;
RX   PubMed=19251847; DOI=10.1128/jb.01779-08;
RA   Slater S.C., Goldman B.S., Goodner B., Setubal J.C., Farrand S.K.,
RA   Nester E.W., Burr T.J., Banta L., Dickerman A.W., Paulsen I., Otten L.,
RA   Suen G., Welch R., Almeida N.F., Arnold F., Burton O.T., Du Z., Ewing A.,
RA   Godsy E., Heisel S., Houmiel K.L., Jhaveri J., Lu J., Miller N.M.,
RA   Norton S., Chen Q., Phoolcharoen W., Ohlin V., Ondrusek D., Pride N.,
RA   Stricklin S.L., Sun J., Wheeler C., Wilson L., Zhu H., Wood D.W.;
RT   "Genome sequences of three Agrobacterium biovars help elucidate the
RT   evolution of multichromosome genomes in bacteria.";
RL   J. Bacteriol. 191:2501-2511(2009).
CC   -!- SIMILARITY: Belongs to the lysopine/nopaline/octopine/opine/vitopine
CC       dehydrogenases family. {ECO:0000305}.
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DR   EMBL; M91608; AAA25044.1; -; Genomic_DNA.
DR   EMBL; CP000637; ACM39698.1; -; Genomic_DNA.
DR   PIR; S30109; S30109.
DR   RefSeq; WP_012649057.1; NC_011982.1.
DR   AlphaFoldDB; Q04554; -.
DR   SMR; Q04554; -.
DR   EnsemblBacteria; ACM39698; ACM39698; Avi_8271.
DR   KEGG; avi:Avi_8271; -.
DR   HOGENOM; CLU_056511_0_0_5; -.
DR   OMA; LMMLMNA; -.
DR   OrthoDB; 427052at2; -.
DR   Proteomes; UP000001596; Plasmid pTiS4.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1040.10; -; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003421; Opine_DH.
DR   Pfam; PF02317; Octopine_DH; 1.
DR   SUPFAM; SSF48179; SSF48179; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
KW   Crown gall tumor; Oxidoreductase; Plasmid; Reference proteome.
FT   CHAIN           1..360
FT                   /note="Vitopine synthase"
FT                   /id="PRO_0000179981"
SQ   SEQUENCE   360 AA;  39700 MW;  2C707453F971BA30 CRC64;
     MSKVAILGAG NLALTFAGDI ARRLNEEVTA VIWAPTTNRR NFNEVRGIGT LELVGPDYEG
     AFTPQLEDDL EAAILDAEFI FLTVPTLAQE GILRELVKFD LSETVLIALP GSATSLTCKN
     ILFPSHSPVA VIESTTSPYA CRRIGERVHM LGVKACFEVA ATSLLSNDLT SRFEALFPNR
     LQWYKDAASI FFSNTNPVVH PPGILVAKDA IENGMSPLPK FYREFVPAAI ERVQELDNER
     LEIIAALGLE SETGFTYSKK WYGGQATEWK EFFETYEGYA EVGTPTTMHH RYLTEDVKHI
     MVLWVQIAEV AGVQVPAMKS VIKEAGNVLY EDLFMTGRTL ASMNLGGANP YRIVDALNGN