ID   VIT1_SOLIN              Reviewed;        1641 AA.
AC   Q7Z1M0;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=Vitellogenin-1 {ECO:0000303|PubMed:11249942};
DE   AltName: Full=Vitellogenin {ECO:0000312|EMBL:AAP47155.1};
DE            Short=VG {ECO:0000303|PubMed:11249942};
DE   Flags: Precursor;
OS   Solenopsis invicta (Red imported fire ant) (Solenopsis wagneri).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Myrmicinae; Solenopsis.
OX   NCBI_TaxID=13686;
RN   [1] {ECO:0000312|EMBL:AAP47155.1}
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Fat body {ECO:0000312|EMBL:AAP47155.1};
RA   Lewis D.K., Chen M.-E., Vinson S.B., Keeley L.L.;
RT   "Cloning and characterization of the vitellogenin cDNA from the imported
RT   fire ant Solenopsis invicta (Formicidae: Apocrita).";
RL   Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000305}
RP   SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RX   PubMed=11249942; DOI=10.1016/s0022-1910(00)00155-4;
RA   Lewis D.K., Campbell J.Q., Sowa S.M., Chen M.-E., Vinson S.B., Keeley L.L.;
RT   "Characterization of vitellogenin in the red imported fire ant, Solenopsis
RT   invicta (Hymenoptera: Apocrita: Formicidae).";
RL   J. Insect Physiol. 47:543-551(2001).
CC   -!- FUNCTION: Precursor of the egg-yolk proteins that are sources of
CC       nutrients during embryonic development. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:11249942}.
CC   -!- TISSUE SPECIFICITY: Hemolymph. {ECO:0000269|PubMed:11249942}.
CC   -!- DEVELOPMENTAL STAGE: Abundantly present in reproductive females but is
CC       present to a lesser degree in other female caste members (alate, virgin
CC       queens; and workers). Not expressed in males.
CC       {ECO:0000269|PubMed:11249942}.
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DR   EMBL; AF512520; AAP47155.1; -; mRNA.
DR   AlphaFoldDB; Q7Z1M0; -.
DR   SMR; Q7Z1M0; -.
DR   PRIDE; Q7Z1M0; -.
DR   GO; GO:0005576; C:extracellular region; IDA:UniProtKB.
DR   GO; GO:0005319; F:lipid transporter activity; IEA:InterPro.
DR   GO; GO:0045735; F:nutrient reservoir activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.20; -; 1.
DR   Gene3D; 2.30.230.10; -; 1.
DR   InterPro; IPR015819; Lipid_transp_b-sht_shell.
DR   InterPro; IPR011030; Lipovitellin_superhlx_dom.
DR   InterPro; IPR015816; Vitellinogen_b-sht_N.
DR   InterPro; IPR015255; Vitellinogen_open_b-sht.
DR   InterPro; IPR001747; Vitellogenin_N.
DR   InterPro; IPR001846; VWF_type-D.
DR   Pfam; PF09172; DUF1943; 1.
DR   Pfam; PF01347; Vitellogenin_N; 1.
DR   Pfam; PF00094; VWD; 1.
DR   SMART; SM01169; DUF1943; 1.
DR   SMART; SM00638; LPD_N; 1.
DR   SMART; SM00216; VWD; 1.
DR   SUPFAM; SSF48431; SSF48431; 1.
DR   SUPFAM; SSF56968; SSF56968; 2.
DR   PROSITE; PS51211; VITELLOGENIN; 1.
DR   PROSITE; PS51233; VWFD; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Glycoprotein; Secreted; Signal; Storage protein.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..1641
FT                   /note="Vitellogenin-1"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000378059"
FT   DOMAIN          19..790
FT                   /note="Vitellogenin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00557"
FT   DOMAIN          1410..1597
FT                   /note="VWFD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00580"
FT   REGION          322..372
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1594..1641
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        322..337
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        338..356
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        357..372
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        344
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        549
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        566
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        831
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        875
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        898
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1001
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1053
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1268
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1393
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1396
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1505
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1523
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        172..211
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00557,
FT                   ECO:0000255|PROSITE-ProRule:PRU00580"
FT   DISULFID        1435..1596
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00580"
SQ   SEQUENCE   1641 AA;  186288 MW;  0A557609857DEEB3 CRC64;
     MWYLAFLLII GAYAADHAWE TGNEYHYLIE SRTLTVLDKL SQQFSGIVIK GGLTIQVKSP
     DTLQAVVSKT QYAPVHKTLE NWNDEIADLK FDELSMSGKS FEIKLKHGVI RDVLIDQDVL
     TWEVNLIKSI VSQLQVDLQG ENVIASSDNQ IPDDSQPFGV YKAMEDSVGG KCEVLYSITP
     VPENFDSIPF PNLRKDGLNF FVTKTKNYNK CEQQMAYHSG ITDKMNWKLG SNDGVLSRSS
     TSSIIISGNV KHFTIQSSLT TSEIFVRSKL HDTYSSAVYD SVKLTLDRMN QISNPMSASN
     NLVSTGNLVY IYNNPFSNQR KLRQPSVSLN SMEARSSENS NEENRSDDDR SNFLSNSGEE
     REYLQSKPTL NEAPESPLLP YFIGYKGESI QKSEDITSVA ARFIAQIAWN LETSPVNAFN
     FSPSTEYIEP CIILIRLIRT MNVEQIAELE NKLSDPIYHL QGNKLPTEYK KSYDKTTWDI
     FFNAVVSAGT GPALISIKNM IKNGQLKDTQ AAMIISKIPK TALTPTSEYV NKFFELITDE
     QVTKQRFLNT SALLAFAELV RYTQSNRSIH YPVHSFGHMV SKQDNALLET YIPYMANQLT
     EAIKDGDSRR IQTYIMALGN FGHPKVLSVF EPYLEGTLPA STFQRLMMVV SLNRLSENFP
     RLARSVAFKI YMNIMEAYEL RCAAVYVVMK TNPPLVMLQR MAEFTNQDQD RHVNSVIKTN
     IDALANLEQP EFQDLAAKAR IARELLNPHI DTESYSQGFL FKKIIPSLNM AEITILQIIG
     SQDTTVPKSS YLNIYQSYGG FNLPPSRMSY EISSFRALLD MWYEMPWMIE NETQKKLIIE
     ETIEKLGIKG EDPVQFEGNI FVNTLYSSQF SPLDNNTIEE TINAFKRIIS SWQRSSKNFT
     SENINYLHYY DMTVAFPTES GLPFIYTLTV PKLLRINIGG GHKGSKTEHF KELTAAGYIM
     VHEKVQSRIG FVTPFEHRHY VAGIDTNTRL VTPLGLSISV NTTEENKKFK LTLQPSKYIR
     YGTGHSTVHF SVVPYTARNN ILDLEHDFSK QDNDTLPVHT KEPHEIHFYI SNWMFVAKSD
     LIDSKASEKQ GMEAIKETVN LFCNSRGAYY RRFDGLMYFG EVRIRASYDF AKLDSDSSEA
     TIPTIVNKEP DSEERKKQFL KEVGKNMNSA YGYVFDMSID QGFDVQVFTL AYSYSQIDHK
     SQALFYWNVQ SVDDPKIYAE LGAIGYVKSK SISLNPEKAL EQIPNDEFKA EIRLGNNFNE
     EMIKLEGNWT RTDDVKDMAM KSEIVKKCRQ DMKQGNILLP ACQKANKLIN QKDLLMMSID
     TTSDILYASA NRGILWIQSL ISENYVETMN LRSSSKNTID MEIKMLPDND DAKISLRTSQ
     ADVSFSLKDI IGNDSNVSMK DTFKEQLDDE SVCVLDKTHA VTFDGKVYPL KLGKCWHVMM
     TIYPKRDPNN FEKTLSIPSD MRAIVMAQEM DDGSKQIKMI LGDQEVHLQK SGDCLEASVD
     GETANFSDHK SHQEKDFEIY GSNETITVFS PTYEITVEYD GEHILLMISD NYLNAVRGLC
     GNYDTQPNND FIIPENCILT KAEEFAATYA MTQESCQGPA PENKRKAEQS TCMSRSYRPS
     DVISDREAGR SSTKNRGWGY H