VITB1_XENLA
ID VITB1_XENLA Reviewed; 71 AA.
AC P19010;
DT 01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1990, sequence version 1.
DT 25-MAY-2022, entry version 71.
DE RecName: Full=Vitellogenin-B1;
DE Short=VTG B1;
DE Flags: Precursor; Fragment;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=6504704; DOI=10.1093/nar/12.22.8595;
RA Germond J.-E., Walker P., ten Heggeler B., Brown-Luedi M., de Bony E.,
RA Wahli W.;
RT "Evolution of vitellogenin genes: comparative analysis of the nucleotide
RT sequences downstream of the transcription initiation site of four Xenopus
RT laevis and one chicken gene.";
RL Nucleic Acids Res. 12:8595-8609(1984).
RN [2]
RP PROTEIN SEQUENCE OF 16-25.
RX PubMed=8185593; DOI=10.1006/bbrc.1994.1607;
RA Montorzi M., Falchuk K.H., Vallee B.L.;
RT "Xenopus laevis vitellogenin is a zinc protein.";
RL Biochem. Biophys. Res. Commun. 200:1407-1413(1994).
CC -!- FUNCTION: Precursor of the major egg-yolk proteins that are sources of
CC nutrients during early development of oviparous organisms.
CC -!- TISSUE SPECIFICITY: Produced by the liver, secreted into the blood and
CC then sequestered by receptor mediated endocytosis into growing oocytes,
CC where it is generally cleaved, giving rise to the respective yolk
CC components.
CC -!- INDUCTION: By steroids (estrogen).
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DR EMBL; X01170; CAA25616.1; -; Genomic_DNA.
DR PIR; C23876; C23876.
DR AlphaFoldDB; P19010; -.
DR SMR; P19010; -.
DR Proteomes; UP000186698; Genome assembly.
DR GO; GO:0005319; F:lipid transporter activity; IEA:InterPro.
DR GO; GO:0045735; F:nutrient reservoir activity; IEA:UniProtKB-KW.
DR Gene3D; 2.30.230.10; -; 1.
DR InterPro; IPR015819; Lipid_transp_b-sht_shell.
DR InterPro; IPR015816; Vitellinogen_b-sht_N.
DR InterPro; IPR001747; Vitellogenin_N.
DR Pfam; PF01347; Vitellogenin_N; 1.
DR SUPFAM; SSF56968; SSF56968; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Phosphoprotein; Reference proteome; Signal;
KW Storage protein.
FT SIGNAL 1..15
FT /evidence="ECO:0000269|PubMed:8185593"
FT CHAIN 16..>71
FT /note="Vitellogenin-B1"
FT /id="PRO_0000041589"
FT DOMAIN 24..>71
FT /note="Vitellogenin"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00557"
FT NON_TER 71
SQ SEQUENCE 71 AA; 7905 MW; 3FE03A309DD3F39E CRC64;
MRGIILAQLL ALAGSEKSQY EPFFSESKPY VYNYEGIILN GIPENGLARS GIKLNCKAEI
SGYAQRSYML K