ID   VITH3_ORYSJ             Reviewed;         249 AA.
AC   Q84ZM7;
DT   27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Vacuolar iron transporter homolog 3 {ECO:0000305};
DE   AltName: Full=Protein NODULIN-LIKE 3 {ECO:0000305};
GN   OrderedLocusNames=Os08g0153300 {ECO:0000312|EMBL:AP014964},
GN   LOC_Os08g05720 {ECO:0000305};
GN   ORFNames=OJ1066_B03.106 {ECO:0000312|EMBL:BAC55676.1},
GN   OJ1349_D05.127 {ECO:0000312|EMBL:BAC99767.1};
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
CC   -!- FUNCTION: Probable vacuolar iron transporter that may be involved in
CC       the regulation of iron distribution throughout the plant.
CC       {ECO:0000250|UniProtKB:Q6MWE5}.
CC   -!- SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000250|UniProtKB:Q6MWE5};
CC       Multi-pass membrane protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the CCC1 family. {ECO:0000305}.
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DR   EMBL; AP003940; BAC55676.1; -; Genomic_DNA.
DR   EMBL; AP005467; BAC99767.1; -; Genomic_DNA.
DR   EMBL; AP014964; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_015651133.1; XM_015795647.1.
DR   AlphaFoldDB; Q84ZM7; -.
DR   SMR; Q84ZM7; -.
DR   PaxDb; Q84ZM7; -.
DR   PRIDE; Q84ZM7; -.
DR   GeneID; 107282079; -.
DR   KEGG; osa:107282079; -.
DR   InParanoid; Q84ZM7; -.
DR   OrthoDB; 1353644at2759; -.
DR   Proteomes; UP000000763; Chromosome 8.
DR   Proteomes; UP000059680; Chromosome 8.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005381; F:iron ion transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0005384; F:manganese ion transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0030026; P:cellular manganese ion homeostasis; IBA:GO_Central.
DR   GO; GO:0006880; P:intracellular sequestering of iron ion; IBA:GO_Central.
DR   InterPro; IPR008217; Ccc1_fam.
DR   PANTHER; PTHR31851; PTHR31851; 1.
DR   Pfam; PF01988; VIT1; 2.
PE   3: Inferred from homology;
KW   Ion transport; Iron; Iron transport; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport; Vacuole.
FT   CHAIN           1..249
FT                   /note="Vacuolar iron transporter homolog 3"
FT                   /id="PRO_0000411014"
FT   TOPO_DOM        1..74
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        75..95
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        96..102
FT                   /note="Vacuolar"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        103..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        124..166
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        167..187
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        188..193
FT                   /note="Vacuolar"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        194..214
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        215..226
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        227..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        248..249
FT                   /note="Vacuolar"
FT                   /evidence="ECO:0000255"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..16
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   249 AA;  25100 MW;  58142D594638B2F0 CRC64;
     MAMQMNSVVH VSTSPSPSPA TSPPPEGKQE HGEVAAVHVV GVGDDEAVMV VKDEEAFGGG
     GVDYSGRAQW LRAAVLGAND GLVSVASLMI GVGAVSESGR AMLVSGVAGL VAGACSMAIG
     EFVSVYAQYD IEVAAARRRR RQRRRRCDGD GEEEGSGRLP SPFKAAAASA LAFTVGALLP
     LLAGGFVRPW APRVAAVCAA TSAALAGFGA LGAALGGASP ARSAARVLLG GWAAMAACYG
     VLRLFANLY