VITH4_ORYSJ
ID VITH4_ORYSJ Reviewed; 216 AA.
AC Q53PN2; A0A0P0XZN4;
DT 27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT 27-JUL-2011, sequence version 2.
DT 03-AUG-2022, entry version 64.
DE RecName: Full=Vacuolar iron transporter homolog 4 {ECO:0000305};
DE AltName: Full=Protein NODULIN-LIKE 4 {ECO:0000305};
GN OrderedLocusNames=Os11g0161900 {ECO:0000312|EMBL:BAT12806.1},
GN LOC_Os11g06310 {ECO:0000312|EMBL:ABA91658.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG The rice chromosomes 11 and 12 sequencing consortia;
RT "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT genes and recent gene duplications.";
RL BMC Biol. 3:20-20(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
CC -!- FUNCTION: Probable vacuolar iron transporter that may be involved in
CC the regulation of iron distribution throughout the plant.
CC {ECO:0000250|UniProtKB:Q6MWE5}.
CC -!- SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000250|UniProtKB:Q6MWE5};
CC Multi-pass membrane protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the CCC1 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAX95090.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=ABA91658.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=BAT12806.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC120533; AAX95090.1; ALT_FRAME; Genomic_DNA.
DR EMBL; DP000010; ABA91658.1; ALT_FRAME; Genomic_DNA.
DR EMBL; AP014967; BAT12806.1; ALT_SEQ; Genomic_DNA.
DR AlphaFoldDB; Q53PN2; -.
DR SMR; Q53PN2; -.
DR STRING; 4530.OS11T0161900-00; -.
DR PaxDb; Q53PN2; -.
DR PRIDE; Q53PN2; -.
DR EnsemblPlants; Os11t0161900-00; Os11t0161900-00; Os11g0161900.
DR Gramene; Os11t0161900-00; Os11t0161900-00; Os11g0161900.
DR eggNOG; KOG4473; Eukaryota.
DR HOGENOM; CLU_038957_5_1_1; -.
DR InParanoid; Q53PN2; -.
DR Proteomes; UP000000763; Chromosome 11.
DR Proteomes; UP000059680; Chromosome 11.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005381; F:iron ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0005384; F:manganese ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0030026; P:cellular manganese ion homeostasis; IBA:GO_Central.
DR GO; GO:0006880; P:intracellular sequestering of iron ion; IBA:GO_Central.
DR InterPro; IPR008217; Ccc1_fam.
DR PANTHER; PTHR31851; PTHR31851; 1.
DR Pfam; PF01988; VIT1; 2.
PE 3: Inferred from homology;
KW Ion transport; Iron; Iron transport; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport; Vacuole.
FT CHAIN 1..216
FT /note="Vacuolar iron transporter homolog 4"
FT /id="PRO_0000411015"
FT TOPO_DOM 1..36
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 37..57
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 58..65
FT /note="Vacuolar"
FT /evidence="ECO:0000255"
FT TRANSMEM 66..86
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 87..134
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 135..155
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 156..157
FT /note="Vacuolar"
FT /evidence="ECO:0000255"
FT TRANSMEM 158..178
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 179..190
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 191..211
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 212..216
FT /note="Vacuolar"
FT /evidence="ECO:0000255"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 216 AA; 21236 MW; DD5E4CC796D2E329 CRC64;
MAATNGDAEL TVAEEAKEEE EATDDGGGGV SSQWLRAAVL GASDGLVSTA ALMLGIGAAR
PADARAVLLS GLAGLVAGAC SMAIGEYVSV HVQLDVELAD LERRRRRGGP APAGLGLHAA
AAAVSRPGQA AAASALSFAA GAALPLLAAW FVAGAYRVRV VVVVATASLA LAAFGAAGAR
LGRAPGGRAG LRVVVGGLLA MAATYGVMKL FRTHGV
