ID   VIUB_VIBCH              Reviewed;         271 AA.
AC   P0C6Q2; Q56646; Q9JQ01;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   18-MAR-2008, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Vibriobactin utilization protein ViuB;
GN   Name=viuB; OrderedLocusNames=VC_2210;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   -!- FUNCTION: Involved in intracellular removal of iron from iron-
CC       vibriobactin complex. Vibriobactin is an iron-chelating compound
CC       involved in the transport of iron from the bacterial environment into
CC       the cell cytoplasm (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the SIP oxidoreductase family. {ECO:0000305}.
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DR   EMBL; AE003852; AAF95354.1; -; Genomic_DNA.
DR   PIR; C82104; C82104.
DR   RefSeq; NP_231841.1; NC_002505.1.
DR   RefSeq; WP_000064348.1; NZ_LT906614.1.
DR   AlphaFoldDB; P0C6Q2; -.
DR   SMR; P0C6Q2; -.
DR   STRING; 243277.VC_2210; -.
DR   DNASU; 2613249; -.
DR   EnsemblBacteria; AAF95354; AAF95354; VC_2210.
DR   GeneID; 57740836; -.
DR   KEGG; vch:VC_2210; -.
DR   PATRIC; fig|243277.26.peg.2108; -.
DR   eggNOG; COG2375; Bacteria.
DR   HOGENOM; CLU_040923_3_1_6; -.
DR   OMA; PYAWIAG; -.
DR   BioCyc; VCHO:VC2210-MON; -.
DR   Proteomes; UP000000584; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0071949; F:FAD binding; IBA:GO_Central.
DR   GO; GO:0052851; F:ferric-chelate reductase (NADPH) activity; IBA:GO_Central.
DR   GO; GO:0010106; P:cellular response to iron ion starvation; IBA:GO_Central.
DR   GO; GO:0033212; P:iron import into cell; IBA:GO_Central.
DR   GO; GO:0015891; P:siderophore transport; IBA:GO_Central.
DR   GO; GO:0019536; P:vibriobactin metabolic process; ISS:UniProtKB.
DR   Gene3D; 3.40.50.80; -; 1.
DR   InterPro; IPR013113; FAD-bd_9_SIP.
DR   InterPro; IPR017927; FAD-bd_FR_type.
DR   InterPro; IPR039261; FNR_nucleotide-bd.
DR   InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR   InterPro; IPR007037; SIP_C.
DR   InterPro; IPR039374; SIP_fam.
DR   PANTHER; PTHR30157; PTHR30157; 1.
DR   Pfam; PF08021; FAD_binding_9; 1.
DR   Pfam; PF04954; SIP; 1.
DR   SUPFAM; SSF63380; SSF63380; 1.
DR   PROSITE; PS51384; FAD_FR; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Ion transport; Iron; Iron transport; Reference proteome;
KW   Transport.
FT   CHAIN           1..271
FT                   /note="Vibriobactin utilization protein ViuB"
FT                   /id="PRO_0000065871"
FT   DOMAIN          8..131
FT                   /note="FAD-binding FR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00716"
SQ   SEQUENCE   271 AA;  30515 MW;  B6B6AE40ACE6A8EC CRC64;
     MSNEVERVYP RLLDFVRKKY VSKNLLRVTL TGEDLIGFPE DQNGSHIKVF FPNQASGILQ
     LPIREGDKVI WPEHKPVPRA YTVRQYRAQS NELDIDFVVH GEGTPGGGWA LKAQTGSQLG
     LIGPGGPDPL IEPADWHIMA GDLSAVPAIS AILEKMPSQA KGYVFLEVDD IEDKHDISHP
     EQMVIKWLVR DPNQAQPVLA MAIEQLPVPQ GAESLSAFVA GENESVIACR KILRNEYRIA
     RDKIYAIPYW KRGKNEEAYH EERHVVMDEE F