ID   VIUB_VIBVU              Reviewed;         271 AA.
AC   Q56743;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2003, sequence version 2.
DT   25-MAY-2022, entry version 108.
DE   RecName: Full=Vulnibactin utilization protein ViuB;
GN   Name=viuB; OrderedLocusNames=VV2_0837;
OS   Vibrio vulnificus (strain CMCP6).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=216895;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=MO6-24;
RX   PubMed=8698519; DOI=10.1128/iai.64.7.2834-2838.1996;
RA   Litwin C.M., Rayback T.W., Skinner J.;
RT   "Role of catechol siderophore synthesis in Vibrio vulnificus virulence.";
RL   Infect. Immun. 64:2834-2838(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CMCP6;
RA   Rhee J.H., Kim S.Y., Chung S.S., Kim J.J., Moon Y.H., Jeong H., Choy H.E.;
RT   "Complete genome sequence of Vibrio vulnificus CMCP6.";
RL   Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in intracellular removal of iron from iron-
CC       vulnibactin complex. Vulnibactin is an iron-chelating compound involved
CC       in transporting iron from the bacterial environment into the cell
CC       cytoplasm.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the SIP oxidoreductase family. {ECO:0000305}.
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DR   EMBL; U32676; AAB18151.1; -; Genomic_DNA.
DR   EMBL; AE016796; AAO07760.1; -; Genomic_DNA.
DR   RefSeq; WP_011081754.1; NC_004460.2.
DR   AlphaFoldDB; Q56743; -.
DR   SMR; Q56743; -.
DR   EnsemblBacteria; AAO07760; AAO07760; VV2_0837.
DR   KEGG; vvu:VV2_0837; -.
DR   HOGENOM; CLU_040923_3_1_6; -.
DR   OMA; PYAWIAG; -.
DR   Proteomes; UP000002275; Chromosome 2.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   GO; GO:0019536; P:vibriobactin metabolic process; ISS:UniProtKB.
DR   Gene3D; 3.40.50.80; -; 1.
DR   InterPro; IPR013113; FAD-bd_9_SIP.
DR   InterPro; IPR017927; FAD-bd_FR_type.
DR   InterPro; IPR039261; FNR_nucleotide-bd.
DR   InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR   InterPro; IPR007037; SIP_C.
DR   InterPro; IPR039374; SIP_fam.
DR   PANTHER; PTHR30157; PTHR30157; 1.
DR   Pfam; PF08021; FAD_binding_9; 1.
DR   Pfam; PF04954; SIP; 1.
DR   SUPFAM; SSF63380; SSF63380; 1.
DR   PROSITE; PS51384; FAD_FR; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Ion transport; Iron; Iron transport; Transport.
FT   CHAIN           1..271
FT                   /note="Vulnibactin utilization protein ViuB"
FT                   /id="PRO_0000065872"
FT   DOMAIN          8..131
FT                   /note="FAD-binding FR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00716"
FT   CONFLICT        181..182
FT                   /note="EE -> QK (in Ref. 1; AAB18151)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        190
FT                   /note="R -> P (in Ref. 1; AAB18151)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        208
FT                   /note="S -> A (in Ref. 1; AAB18151)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        224
FT                   /note="Q -> H (in Ref. 1; AAB18151)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        235
FT                   /note="N -> S (in Ref. 1; AAB18151)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        270
FT                   /note="V -> A (in Ref. 1; AAB18151)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   271 AA;  30293 MW;  FB24AC4405F738F2 CRC64;
     MSDSPERVYP MLLDFVRKET ISKNLLRVTL TGEDLIGFPE DQNGSHIKVF FPNQASGILQ
     LPVREGDNVI WPEHKPVPRA YSVRQYRAAV NELDIDFVTH GEETPGGGWA LKADIGSQIG
     LIGPAGPDPL IEPADWHIIA GDLSAVPAIS AILEKLPSDA KGYVFIEVDE IEDIHDLVHP
     EEMAINWLMR NPHDAEPALA KAIKQLPSPE KATSLSAFIA GENQSVINCR KILRNDYQIA
     RDKLYAIPYW KRGKTEEAYH DERHDVMDAV Y