ID   VJBR_BRUAB              Reviewed;         259 AA.
AC   Q579W9;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=HTH-type quorum sensing-dependent transcriptional regulator VjbR;
GN   Name=vjbR; OrderedLocusNames=BruAb2_0117;
OS   Brucella abortus biovar 1 (strain 9-941).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=262698;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=9-941;
RX   PubMed=15805518; DOI=10.1128/jb.187.8.2715-2726.2005;
RA   Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z.,
RA   Li L.-L., Kapur V., Alt D.P., Olsen S.C.;
RT   "Completion of the genome sequence of Brucella abortus and comparison to
RT   the highly similar genomes of Brucella melitensis and Brucella suis.";
RL   J. Bacteriol. 187:2715-2726(2005).
CC   -!- FUNCTION: Transcriptional regulator involved in the global control of
CC       Brucella gene expression. Mediates the effects of the quorum sensing
CC       autoinducer C12-HSL (N-dodecanoyl-homoserine lactone) on a large and
CC       diverse number of genes. {ECO:0000250|UniProtKB:Q8YAY5}.
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DR   EMBL; AE017224; AAX75565.1; -; Genomic_DNA.
DR   RefSeq; WP_002966460.1; NC_006933.1.
DR   AlphaFoldDB; Q579W9; -.
DR   SMR; Q579W9; -.
DR   EnsemblBacteria; AAX75565; AAX75565; BruAb2_0117.
DR   GeneID; 45053211; -.
DR   GeneID; 55591850; -.
DR   KEGG; bmb:BruAb2_0117; -.
DR   HOGENOM; CLU_072786_7_0_5; -.
DR   OMA; RESLQWV; -.
DR   Proteomes; UP000000540; Chromosome II.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0009372; P:quorum sensing; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.30.450.80; -; 1.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR005143; TF_LuxR_autoind-bd_dom.
DR   InterPro; IPR036693; TF_LuxR_autoind-bd_dom_sf.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF03472; Autoind_bind; 1.
DR   Pfam; PF00196; GerE; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; SSF46894; 1.
DR   SUPFAM; SSF75516; SSF75516; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Quorum sensing; Transcription; Transcription regulation.
FT   CHAIN           1..259
FT                   /note="HTH-type quorum sensing-dependent transcriptional
FT                   regulator VjbR"
FT                   /id="PRO_0000319925"
FT   DOMAIN          183..248
FT                   /note="HTH luxR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
FT   DNA_BIND        207..226
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
FT   REGION          76..179
FT                   /note="C12-HSL binding"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   259 AA;  28625 MW;  2D845BA0737094CC CRC64;
     MSLDLVHFPN YKKTFFGSSF QSDTLALLTR IRDEIGCRYV THTYRGRVGD CTKVNSADLT
     VLMTLPATWV ARYSSKNYFA IDPVFQEDAP YYRNDTSAIA RDLKEDADIC PAVAELLHDA
     EKHGLGNLFI AVSARNPKGV AGCTVFTFEV EDEDRTQFLA RMRPRLLSLA GIIHGTVCGC
     KDANSVASLL TPREVDCLRW AANGKTDGEI AEILSIARWT VVTYLQNAKI KLNCSNRTSA
     VATALSLGII DMPEVQHLV