VKTG1_MICPY
ID VKTG1_MICPY Reviewed; 35 AA.
AC P0CAR0;
DT 16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT 16-JUN-2009, sequence version 1.
DT 25-MAY-2022, entry version 28.
DE RecName: Full=Kunitz-type serine protease inhibitor G1;
DE Flags: Fragment;
OS Micrurus pyrrhocryptus (Coral snake).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Micrurus.
OX NCBI_TaxID=129468;
RN [1]
RP PROTEIN SEQUENCE, AND MASS SPECTROMETRY.
RC TISSUE=Venom;
RX PubMed=19135468; DOI=10.1016/j.toxicon.2008.12.015;
RA Dokmetjian J.C., Del Canto S., Vinzon S., de Jimenez Bonino M.B.;
RT "Biochemical characterization of the Micrurus pyrrhocryptus venom.";
RL Toxicon 53:375-382(2009).
CC -!- FUNCTION: Serine protease inhibitor. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC -!- PTM: Contains three disulfide bonds. {ECO:0000250}.
CC -!- MASS SPECTROMETRY: Mass=6379; Method=Electrospray;
CC Evidence={ECO:0000269|PubMed:19135468};
CC -!- SIMILARITY: Belongs to the venom Kunitz-type family. {ECO:0000305}.
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DR AlphaFoldDB; P0CAR0; -.
DR SMR; P0CAR0; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR Gene3D; 4.10.410.10; -; 1.
DR InterPro; IPR002223; Kunitz_BPTI.
DR InterPro; IPR036880; Kunitz_BPTI_sf.
DR Pfam; PF00014; Kunitz_BPTI; 1.
DR SUPFAM; SSF57362; SSF57362; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Disulfide bond; Protease inhibitor; Secreted;
KW Serine protease inhibitor; Toxin.
FT CHAIN 1..>35
FT /note="Kunitz-type serine protease inhibitor G1"
FT /id="PRO_0000377472"
FT DOMAIN 6..>35
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00031"
FT NON_TER 35
SQ SEQUENCE 35 AA; 3955 MW; 031BD83C8E65D0F3 CRC64;
KVPAYCKLPP DSGPCKGHFP AFYYDPVSSY CQKFI