VL1_FPVL
ID VL1_FPVL Reviewed; 110 AA.
AC P06456;
DT 01-JAN-1988, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1988, sequence version 1.
DT 02-DEC-2020, entry version 72.
DE RecName: Full=Major capsid protein L1;
DE Flags: Fragment;
GN Name=L1;
OS Avian papillomavirus fpv-l.
OC Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes;
OC Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae;
OC Etapapillomavirus; unclassified Etapapillomavirus.
OX NCBI_TaxID=10577;
OH NCBI_TaxID=8782; Aves.
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=6088809; DOI=10.1128/jvi.51.3.872-875.1984;
RA Moreno-Lopez J., Ahola H., Stenlund A., Osterhaus A., Pettersson U.;
RT "Genome of an avian papillomavirus.";
RL J. Virol. 51:872-875(1984).
CC -!- FUNCTION: Forms an icosahedral capsid with a T=7 symmetry and about 55
CC nm diameter. The capsid is composed of 72 pentamers linked to each
CC other by disulfide bonds and associated with L2 proteins. The capsid
CC encapsulates the genomic DNA, but does not bind DNA. Essential for the
CC initial attachment to the host cell (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Self-assembles into homopentamers. The capsid has an
CC icosahedral symmetry and consists of 72 capsomers, with each capsomer
CC being a pentamer of L1. Interacts with the minor capsid protein L2;
CC this interaction is necessary for viral genome encapsidation (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the papillomaviridae L1 protein family.
CC {ECO:0000305}.
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DR EMBL; K02020; AAA46923.1; -; Genomic_DNA.
DR GO; GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR GO; GO:0019062; P:virion attachment to host cell; IEA:UniProtKB-KW.
DR Gene3D; 2.60.175.20; -; 1.
DR InterPro; IPR002210; Capsid_L1_Papillomavir.
DR InterPro; IPR036973; Capsid_L1_sf_Papillomavir.
DR InterPro; IPR011222; dsDNA_vir_gr_I_capsid.
DR Pfam; PF00500; Late_protein_L1; 1.
DR SUPFAM; SSF88648; SSF88648; 1.
PE 3: Inferred from homology;
KW Capsid protein; Host-virus interaction; Late protein;
KW Viral attachment to host cell; Virion; Virus entry into host cell.
FT CHAIN <1..>110
FT /note="Major capsid protein L1"
FT /id="PRO_0000133481"
FT NON_TER 1
FT NON_TER 110
SQ SEQUENCE 110 AA; 12523 MW; 72B5F0FC69F108B0 CRC64;
EPVPETVPIA SREQIEKNNS AYMACPSGSV ITSDTNLFNR SYWTNNGILW NENLFVTVLD
NSRNVIMKIS SLAEGAQENN ATVYDWKNYY ECVRHVEEYG ISAIVRLCRV