CALC_BRAOB
ID CALC_BRAOB Reviewed; 148 AA.
AC Q6R4R7;
DT 16-MAY-2012, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 68.
DE RecName: Full=Truncated transcription factor CAULIFLOWER C;
DE Short=BobCAL-c;
DE AltName: Full=Agamous-like MADS-box protein CAL-C;
GN Name=CAL-C;
OS Brassica oleracea var. botrytis (Cauliflower).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=3715;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Flower meristem;
RA He Y.-K., Cao W.-G., Shen R.-J., Liu P.-L.;
RL Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP REVIEW, AND GENE FAMILY.
RX PubMed=10835404; DOI=10.1093/genetics/155.2.855;
RA Purugganan M.D., Boyles A.L., Suddith J.I.;
RT "Variation and selection at the CAULIFLOWER floral homeotic gene
RT accompanying the evolution of domesticated Brassica oleracea.";
RL Genetics 155:855-862(2000).
CC -!- FUNCTION: Probable transcription factor that promotes early floral
CC meristem identity in synergy with APETALA1, FRUITFULL and LEAFY. Is
CC required subsequently for the transition of an inflorescence meristem
CC into a floral meristem. Seems to be partially redundant to the function
CC of APETALA1 (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Homodimer capable of binding to CArG-box sequences.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00251}.
CC -!- MISCELLANEOUS: This is a truncated version of CAULIFLOWER that may
CC contribute to the 'cauliflower'-shaped floral meristem (curd). This
CC trait has likely been selected by early farmers during the
CC domestication of modified inflorescence structures.
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DR EMBL; AY514054; AAS67312.1; -; mRNA.
DR AlphaFoldDB; Q6R4R7; -.
DR SMR; Q6R4R7; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0009908; P:flower development; IEA:UniProtKB-KW.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd00265; MADS_MEF2_like; 1.
DR Gene3D; 3.40.1810.10; -; 1.
DR InterPro; IPR033896; MADS_MEF2-like.
DR InterPro; IPR002487; TF_Kbox.
DR InterPro; IPR002100; TF_MADSbox.
DR InterPro; IPR036879; TF_MADSbox_sf.
DR Pfam; PF01486; K-box; 1.
DR Pfam; PF00319; SRF-TF; 1.
DR PRINTS; PR00404; MADSDOMAIN.
DR SMART; SM00432; MADS; 1.
DR SUPFAM; SSF55455; SSF55455; 1.
DR PROSITE; PS51297; K_BOX; 1.
DR PROSITE; PS00350; MADS_BOX_1; 1.
DR PROSITE; PS50066; MADS_BOX_2; 1.
PE 2: Evidence at transcript level;
KW Activator; Coiled coil; Developmental protein; Differentiation;
KW DNA-binding; Flowering; Nucleus; Transcription; Transcription regulation.
FT CHAIN 1..148
FT /note="Truncated transcription factor CAULIFLOWER C"
FT /id="PRO_0000417142"
FT DOMAIN 1..61
FT /note="MADS-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00251"
FT DOMAIN 90..148
FT /note="K-box; partial"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00629"
SQ SEQUENCE 148 AA; 17489 MW; 411A67BDBFD9FA03 CRC64;
MGRGRVEMKR IENKINRQVT FSKRRAGLLK KAHEISILCD AEVSLIVFSH KGKLFEYSSE
SCMEKVLERY ERYSYAEKQL KAPDSHVNAQ TNWSMEYSRL KAKIELWERN QRHYLGEDLE
SISIKELQNL EQQLDTSLKH IPSRKVCK
