ID   VLF1_NPVHZ              Reviewed;         415 AA.
AC   Q82484;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   29-SEP-2021, entry version 61.
DE   RecName: Full=Very late expression factor 1;
GN   Name=VLF-1;
OS   Heliothis zea nuclear polyhedrosis virus (HzSNPV) (Helicoverpa zea single
OS   nucleocapsid nuclear polyhedrosis virus).
OC   Viruses; Naldaviricetes; Lefavirales; Baculoviridae; Alphabaculovirus;
OC   unclassified Alphabaculovirus.
OX   NCBI_TaxID=28290;
OH   NCBI_TaxID=7088; Lepidoptera (butterflies and moths).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Elkar;
RX   PubMed=7964631; DOI=10.1099/0022-1317-75-11-3211;
RA   Cowan P.J., Bulach D.M., Goodge K., Robertson A., Tribe D.E.;
RT   "Nucleotide sequence of the polyhedrin gene region of Helicoverpa zea
RT   single nucleocapsid nuclear polyhedrosis virus: placement of the virus in
RT   lepidopteran nuclear polyhedrosis virus group II.";
RL   J. Gen. Virol. 75:3211-3218(1994).
CC   -!- FUNCTION: Involved in very late gene activation. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC       {ECO:0000255|PROSITE-ProRule:PRU01246}.
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DR   EMBL; U11242; AAA58702.1; -; Genomic_DNA.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.443.10; -; 1.
DR   InterPro; IPR011010; DNA_brk_join_enz.
DR   InterPro; IPR013762; Integrase-like_cat_sf.
DR   InterPro; IPR002104; Integrase_catalytic.
DR   Pfam; PF00589; Phage_integrase; 1.
DR   SUPFAM; SSF56349; SSF56349; 1.
DR   PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE   3: Inferred from homology;
KW   DNA recombination; Transcription; Transcription regulation.
FT   CHAIN           1..415
FT                   /note="Very late expression factor 1"
FT                   /id="PRO_0000132877"
FT   DOMAIN          171..357
FT                   /note="Tyr recombinase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   REGION          339..415
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        348..366
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        371..415
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        214
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        242
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        307
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        330
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        343
FT                   /note="O-(3'-phospho-DNA)-tyrosine intermediate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
SQ   SEQUENCE   415 AA;  48337 MW;  EC081F917704F0FE CRC64;
     MNNHPATLRN ESSFNYWKSR IQNHDKFDEI FELTTDRQRC TPDEVKNNSL WSQYMFCKPF
     APTTLKSYKS RFIKLIYCLI DDEYLNNYYD THTLNKEFNS IVQQQPLIKP EELCRRMLEL
     RSVTKETLQL TINFYTNTMN LPEYKIPKQV MLPRDKEIKN IKNNEKNIVL REIINTILDC
     IEKKIKHLSS EFVHDRGLIR GAIVFCIMLG TGMRINRSRH LSVDDLNTLI KRGKLRQAIG
     LKRKKHRTSN SLNSIKQKPL ELAREIYIKN PNILNISKNT STPFKDFKRL LKEANVEMDR
     PRSNMIRHYL SSNLYNNGMP LQKVARLMNH ESSASTRHYL NKYDVGVDES DDNDEDDDDD
     ENDDRIIDEN PSGANISNYD INNSSSGNSS SNNTSGNDFN NNISSGDDAD LLSFN