VLTF2_VACCA
ID VLTF2_VACCA Reviewed; 150 AA.
AC O57216;
DT 21-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 07-APR-2021, entry version 40.
DE RecName: Full=Viral late gene transcription factor 2;
DE Short=VLTF-2;
DE AltName: Full=Trans-activator protein A1;
GN Name=VLTF2; OrderedLocusNames=MVA111L, ACAM3000_MVA_111;
OS Vaccinia virus (strain Ankara) (VACV).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX NCBI_TaxID=126794;
OH NCBI_TaxID=9606; Homo sapiens (Human).
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=9601507; DOI=10.1006/viro.1998.9123;
RA Antoine G., Scheiflinger F., Dorner F., Falkner F.G.;
RT "The complete genomic sequence of the modified vaccinia Ankara strain:
RT comparison with other orthopoxviruses.";
RL Virology 244:365-396(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate Acambis 3000;
RA Esposito J.J., Frace M., Sammons S.A., Olsen-Rasmussen M.S., Osborne J.,
RA Khristova M., Wohlhueter R.M.;
RL Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Acts with RNA polymerase to initiate transcription from late
CC gene promoters. {ECO:0000250}.
CC -!- SUBUNIT: Interacts with itself. Interacts with the late transcription
CC factors VLTF-1 (By similarity). {ECO:0000250}.
CC -!- DEVELOPMENTAL STAGE: Intermediate stages of infection.
CC -!- SIMILARITY: Belongs to the chordopoxvirinae VLTF-2 family.
CC {ECO:0000305}.
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DR EMBL; U94848; AAB96454.1; -; Genomic_DNA.
DR EMBL; AY603355; AAT10509.1; -; Genomic_DNA.
DR PIR; T37387; T37387.
DR Proteomes; UP000159908; Genome.
DR Proteomes; UP000172909; Genome.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR InterPro; IPR004975; Poxvirus_VLTF2.
DR InterPro; IPR010507; Znf_MYM.
DR Pfam; PF03295; Pox_TAA1; 1.
DR Pfam; PF06467; zf-FCS; 1.
PE 2: Evidence at transcript level;
FT CHAIN 1..150
FT /note="Viral late gene transcription factor 2"
FT /id="PRO_0000099170"
SQ SEQUENCE 150 AA; 16934 MW; 4DE0A9260612138D CRC64;
MAKRVSLPDV VISAPKAVFK PAKEEALACI LPKYYKSMAD VSIKTNSVID KCWFCNQDLV
FRPISIETFK GGEVGYFCSK ICRDSLASMV KSHVALREEP KISLLPLVFY EDKEKVINTI
NLLRDKDGVY GSCYFKENSQ IIDISLRSLL