ID   VLTF2_VACCC             Reviewed;         150 AA.
AC   P20982;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   29-SEP-2021, entry version 66.
DE   RecName: Full=Viral late gene transcription factor 2;
DE            Short=VLTF-2;
DE   AltName: Full=Trans-activator protein A1;
GN   Name=VLTF2; ORFNames=A1L;
OS   Vaccinia virus (strain Copenhagen) (VACV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10249;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=2219722; DOI=10.1016/0042-6822(90)90294-2;
RA   Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA   Paoletti E.;
RT   "The complete DNA sequence of vaccinia virus.";
RL   Virology 179:247-266(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA   Paoletti E.;
RT   "Appendix to 'The complete DNA sequence of vaccinia virus'.";
RL   Virology 179:517-563(1990).
CC   -!- FUNCTION: Acts with RNA polymerase to initiate transcription from late
CC       gene promoters. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with itself. Interacts with the late transcription
CC       factors VLTF-1 (By similarity). {ECO:0000250}.
CC   -!- DEVELOPMENTAL STAGE: Intermediate stages of infection.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae VLTF-2 family.
CC       {ECO:0000305}.
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DR   EMBL; M35027; AAA48116.1; -; Genomic_DNA.
DR   PIR; C42517; C42517.
DR   Proteomes; UP000008269; Genome.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   InterPro; IPR004975; Poxvirus_VLTF2.
DR   InterPro; IPR010507; Znf_MYM.
DR   Pfam; PF03295; Pox_TAA1; 1.
DR   Pfam; PF06467; zf-FCS; 1.
PE   2: Evidence at transcript level;
KW   Activator; Late protein; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..150
FT                   /note="Viral late gene transcription factor 2"
FT                   /id="PRO_0000099171"
SQ   SEQUENCE   150 AA;  16950 MW;  4DF6D39AC068AF5D CRC64;
     MAKRVSLPDV VISAPKAVFK PAKEEALACI LPKYYKSMAD VSIKTNSVID KCWFCNQDLV
     FRPISIETYK GGEVGYFCSK ICRDSLASMV KSHVALREEP KISLLPLVFY EDKEKVINTI
     NLLRDKDGVY GSCYFKENSQ IIDISLRSLL