VMAC_RAT
ID VMAC_RAT Reviewed; 171 AA.
AC Q6QZQ4;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 65.
DE RecName: Full=Vimentin-type intermediate filament-associated coiled-coil protein;
GN Name=Vmac;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RC STRAIN=Sprague-Dawley;
RX PubMed=14985129; DOI=10.1016/j.bbrc.2004.01.169;
RA Yamamoto Y., Irie K., Kurihara H., Sakai T., Takai Y.;
RT "Vmac: a novel protein associated with vimentin-type intermediate filament
RT in podocytes of rat kidney.";
RL Biochem. Biophys. Res. Commun. 315:1120-1125(2004).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:14985129}.
CC Note=Colocalizes with vimentin-type intermediate filaments.
CC -!- TISSUE SPECIFICITY: Expressed in brain, heart, kidney, liver, lung,
CC skeletal muscle, spleen and testis. Within the kidney expression is
CC pronounced within glomeruli. {ECO:0000269|PubMed:14985129}.
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DR EMBL; AY521229; AAS66000.1; -; mRNA.
DR RefSeq; NP_001001720.1; NM_001001720.1.
DR AlphaFoldDB; Q6QZQ4; -.
DR SMR; Q6QZQ4; -.
DR PaxDb; Q6QZQ4; -.
DR PRIDE; Q6QZQ4; -.
DR GeneID; 363327; -.
DR KEGG; rno:363327; -.
DR CTD; 400673; -.
DR RGD; 1303340; Vmac.
DR eggNOG; ENOG502SD5N; Eukaryota.
DR HOGENOM; CLU_136281_0_0_1; -.
DR InParanoid; Q6QZQ4; -.
DR OMA; KICQRRP; -.
DR OrthoDB; 1518511at2759; -.
DR PhylomeDB; Q6QZQ4; -.
DR PRO; PR:Q6QZQ4; -.
DR Proteomes; UP000002494; Chromosome 9.
DR Bgee; ENSRNOG00000048897; Expressed in adult mammalian kidney and 19 other tissues.
DR GO; GO:0005737; C:cytoplasm; IDA:RGD.
DR GO; GO:0045098; C:type III intermediate filament; IDA:RGD.
DR InterPro; IPR038809; VMAC.
DR PANTHER; PTHR34707:SF1; PTHR34707:SF1; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Cytoplasm; Reference proteome.
FT CHAIN 1..171
FT /note="Vimentin-type intermediate filament-associated
FT coiled-coil protein"
FT /id="PRO_0000319068"
FT REGION 126..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 7..98
FT /evidence="ECO:0000255"
SQ SEQUENCE 171 AA; 18844 MW; F8205667ACCFB926 CRC64;
MSAPPPLQIR EANAHLAAVH RRAAELERRL LAAERTMRAQ AERLACQDQQ LRAALDELGR
AKDREIFTLQ EQLLSSEATV RSLQAAVEQR DQMIQELQPR ADLLQDITRQ RPPLAALLAT
LEEAEELGPL PSSHSHGAQL LPDGPGPPLG NSMREEEGQD DQQPAVFGTT V