ID   VME1_WBV24              Reviewed;         227 AA.
AC   Q008X3;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   14-NOV-2006, sequence version 1.
DT   02-JUN-2021, entry version 28.
DE   RecName: Full=Membrane protein;
DE            Short=M protein;
DE   AltName: Full=E1 glycoprotein;
DE   AltName: Full=Matrix glycoprotein;
DE   AltName: Full=Membrane glycoprotein;
GN   Name=M;
OS   White bream virus (isolate Blicca bjoerkna L./Germany/DF24/00) (WBV).
OC   Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC   Nidovirales; Tornidovirineae; Tobaniviridae; Piscanivirinae; Bafinivirus;
OC   Blicbavirus.
OX   NCBI_TaxID=766180;
OH   NCBI_TaxID=58317; Blicca bjoerkna (white bream).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=16987966; DOI=10.1128/jvi.01758-06;
RA   Schuetze H., Ulferts R., Schelle B., Bayer S., Granzow H., Hoffmann B.,
RA   Mettenleiter T.C., Ziebuhr J.;
RT   "Characterization of White bream virus reveals a novel genetic cluster of
RT   nidoviruses.";
RL   J. Virol. 80:11598-11609(2006).
CC   -!- FUNCTION: Component of the viral envelope that plays a central role in
CC       virus morphogenesis and assembly via its interactions with other viral
CC       proteins. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with many viral proteins in infected cells.
CC       Interacts with envelope E protein in the budding compartment of the
CC       host cell, which is located between endoplasmic reticulum and the Golgi
CC       complex. Forms a complex with HE and S proteins. Interacts with
CC       nucleocapsid N protein. This interaction probably participates in the
CC       viral mRNA packaging into the virus (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}. Host Golgi apparatus membrane
CC       {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the torovirinae M protein family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DQ898157; ABI97396.1; -; Genomic_RNA.
DR   RefSeq; YP_803216.1; NC_008516.1.
DR   GeneID; 4443110; -.
DR   KEGG; vg:4443110; -.
DR   Proteomes; UP000000680; Genome.
DR   GO; GO:0044178; C:host cell Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0019031; C:viral envelope; IEA:UniProtKB-KW.
DR   GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0039660; F:structural constituent of virion; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Glycoprotein; Host Golgi apparatus; Host membrane; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix;
KW   Viral envelope protein; Viral matrix protein; Virion.
FT   CHAIN           1..227
FT                   /note="Membrane protein"
FT                   /id="PRO_0000408905"
FT   TOPO_DOM        1..42
FT                   /note="Virion surface"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        43..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        64..66
FT                   /note="Intravirion"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        88..95
FT                   /note="Virion surface"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        96..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        117..227
FT                   /note="Intravirion"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   227 AA;  24992 MW;  C02BE44A6D3C9A97 CRC64;
     MSANQSQSIS GALSQLTSSN SFYGGNVDIL SSLLQFNLMW ASVFLLAIHL LVNTLVYYIP
     FVGRLPMVGT INNLIWFVAT LLLIILVYVA SDNIIVKAFG GILVLLLLLS VIILLYKSTM
     FFITLYYHQS FMVAARGPTV LSVNGSHYSL DFIPSAVIIT TRQGKCFYNG HDLGSCSADS
     CSVILFSGRY RSEFEVHRNS PKKLTVDVCG YTTLLTVYTP KASKTDV